Casein kinase 1, alpha 1 explained

Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene.^[1]

Interactions

Casein kinase 1, alpha 1 has been shown to interact with Centaurin, alpha 1^{[2] [3]} and AXIN1.^[4]

See also

• Casein kinase 1

Further reading

• Veis A, Sfeir C, Wu CB . Phosphorylation of the proteins of the extracellular matrix of mineralized tissues by casein kinase-like activity . Critical Reviews in Oral Biology and Medicine . 8 . 4 . 360–79 . 1998 . 9391750 . 10.1177/10454411970080040101 . free .
• Giaccia AJ, Kastan MB . The complexity of p53 modulation: emerging patterns from divergent signals . Genes & Development . 12 . 19 . 2973–83 . Oct 1998 . 9765199 . 10.1101/gad.12.19.2973 . free .

Notes and References

1. Tapia C, Featherstone T, Gómez C, Taillon-Miller P, Allende CC, Allende JE . Cloning and chromosomal localization of the gene coding for human protein kinase CK1 . FEBS Letters . 349 . 2 . 307–12 . Aug 1994 . 8050587 . 10.1016/0014-5793(94)00679-2 . 19071414 . free .
2. Dubois T, Howell S, Zemlickova E, Aitken A . Identification of casein kinase Ialpha interacting protein partners . FEBS Letters . 517 . 1–3 . 167–71 . Apr 2002 . 12062430 . 10.1016/S0014-5793(02)02614-5 . 84792445 . free .
3. Dubois T, Kerai P, Zemlickova E, Howell S, Jackson TR, Venkateswarlu K, Cullen PJ, Theibert AB, Larose L, Roach PJ, Aitken A . Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins . The Journal of Biological Chemistry . 276 . 22 . 18757–64 . Jun 2001 . 11278595 . 10.1074/jbc.M010005200 . free .
4. Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC . Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways . The Journal of Biological Chemistry . 277 . 20 . 17706–12 . May 2002 . 11884395 . 10.1074/jbc.M111982200 . free .