| Casa de Estudillo | |
| Location: | 550 W Estudillo Ave., San Leandro, California |
| Designation1: | California |
| Designation1 Number: | 279 |
| Coordinates: | 37.7234°N -122.1601°W |
Casa de Estudillo was a 19th-century adobe house, located in San Leandro, California. It was built by Don José Joaquín Estudillo, a member of the prominent Estudillo family of California.
It was built around 1850, and was the last home of José Joaquín Estudillo, a member of the prominent Estudillo family of California, and his wife Juana Martínez de Estudillo.
The site is now the location of St. Leander's Church. There is a plaque commemorating the house.