Carotenoid 1,2-hydratase explained

Carotenoid 1,2-hydratase
Ec Number:	4.2.1.131

Carotenoid 1,2-hydratase (CrtC) is an enzyme with systematic name lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming).^{[1] [2]} This enzyme catalyses the following chemical reaction

(1) 1-hydroxy-1,2-dihydrolycopene

\rightleftharpoons lycopene + H₂O

(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene

\rightleftharpoons 1-hydroxy-1,2-dihydrolycopene + H₂O

In Rubrivivax gelatinosus and Thiocapsa roseopersicina both products are formed.

Notes and References

1. Steiger S, Mazet A, Sandmann G . Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus . Archives of Biochemistry and Biophysics . 414 . 1 . 51–8 . June 2003 . 12745254 . 10.1016/s0003-9861(03)00099-7 .
2. Hiseni A, Arends IW, Otten LG . Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina . Applied Microbiology and Biotechnology . 91 . 4 . 1029–36 . August 2011 . 21590288 . 3145076 . 10.1007/s00253-011-3324-1 .