| Carlos Saladrigas Zayas | |
| Order1: | 1st |
| Office1: | Prime Minister of Cuba |
| Term Start1: | 10 October 1940 |
| Term End1: | 16 August 1942 |
| President1: | Fulgencio Batista |
| Predecessor1: | Position Established |
| Successor1: | Ramón Zaydín |
| Birth Date: | 13 October 1900 |
| Birth Place: | Havana, Cuba |
| Death Date: | 15 April 1956 (aged 55) |
| Death Place: | Havana, Cuba |
| Party: | Popular Socialist Party |
| Spouse: | María González-Llorente Esperanza Plasencia Cusa Carrillo |
| Children: | 2 |
| Profession: | Lawyer |
Carlos Saladrigas Zayas (Carlos Eduardo Ramón Saladrigas y Zayas; October 13, 1900 – 15 April 1956) was a Cuban politician and diplomat.
He was an abogado-notario who served as Senator (1936-1940), Minister of Justice (1934), Foreign Minister (1933) and (1955-1956), Prime Minister of Cuba (1940-1942), Ambassador to Great Britain, and presidential candidate in the elections of 1944.
He was the son of Enrique Saladrigas Lunar and María Luisa Zayas y Diago. He married his wife, María de las Mercedes González-Llorente y Martínez in 1923 and they had two children, Gloria and Carlos Saladrigas y González-Llorente. He later married Esperanza Plasencia y del Peso and lastly Cusa Carrillo.