Carlos Caldas Explained

Carlos Caldas
Birth Name:Carlos Manuel Simão da Silva Caldas
Birth Date:27 June 1960
Workplaces:University of CambridgeAddenbrooke's Hospital
Robinson College, Cambridge
Alma Mater:University of Lisbon Medical School
Awards:Fellow of the Academy of Medical Sciences
Spouses:)-->
Partners:)-->
Website:https://www.oncology.cam.ac.uk/directory/c-caldas

Professor Carlos Caldas is a clinician scientist and Professor of Cancer Medicine at the University of Cambridge. He is the Chair of Cancer Medicine at the University of Cambridge, an Honorary Consultant Medical Oncologist at Addenbrooke's Hospital and Director of the Cambridge Breast Cancer Research Unit.[1] [2] He is a fellow of Robinson College, Cambridge[3] and an Emeritus Senior Investigator at the National Institute for Health Research (NIHR).[4]

Education

Professor Carlos Caldas graduated from the University of Lisbon Medical School before training in Internal Medicine in University of Texas Southwestern, Dallas and Medical Oncology at Johns Hopkins Hospital, Baltimore. He then moved to the Institute of Cancer Research, London to complete a research fellowship.

Research and career

Caldas' research focuses on the functional genomics of breast cancer.[5] [6] Caldas led the METABRIC (Molecular Taxonomy of Breast Cancer International Consortium) study, analysing the genome and transcriptome of tumours from nearly 2,000 women and comparing this with long-term clinical information including survival, age and diagnosis. The METABRIC study concluded that breast cancer was at least ten different subtypes, characterised by distinct genomic drivers.[7] [8] In 2019, the team published research showing the subtype a women's breast cancer is initially placed in could predict the likelihood of the tumour returning or metastasising over the next 20 years.[9] [10] [11]

Professor Caldas leads the Personalised Breast Cancer Programme in Cambridge, where woman diagnosed with breast cancer have a sample of their tumour and blood sent for DNA and RNA sequencing. The sequencing results help determine the best course of treatment for patients and can reveal if their tumour is developing resistance to treatment.[12] [13] [14]

Awards and honours

Notes and References

  1. Web site: Prof C Caldas Cambridge University Hospitals. www.cuh.nhs.uk. 2019-08-29.
  2. Web site: Professor Carlos Caldas — Department of Oncology. kla29@cam.ac.uk. www.oncology.cam.ac.uk. 2019-08-29.
  3. https://www.robinson.cam.ac.uk/people/professor-carlos-caldas-fmedsci Caldas's Robinson College webpage
  4. Web site: NIHR Senior Investigators 2020. 2022-02-09. NIHR.
  5. Web site: Carlos Caldas - Google Scholar Citations. scholar.google.co.uk. 2019-08-29.
  6. Web site: Caldas Group. Cancer Research UK Cambridge Institute. 2019-08-29.
  7. Aparicio. Samuel. Caldas. Carlos. Tavaré. Simon. Brenton. James D.. Børresen-Dale. Anne-Lise. Purushotham. Arnie. Ellis. Ian. Murphy. Leigh. Markowetz. Florian. June 2012. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 486. 7403. 346–352. 10.1038/nature10983. 22522925. 1476-4687. 3440846. 2012Natur.486..346..
  8. News: Breast cancer map 'a key moment'. Gallagher. James. 2012-04-18. 2019-08-29.
  9. Curtis. Christina. Caldas. Carlos. Aparicio. Samuel. Rueda. Cristina. Pharoah. Paul D.. Ellis. Ian O.. Purushotham. Arnie. Murphy. Leigh. Green. Andrew R.. March 2019. Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups. Nature. 567. 7748. 399–404. 10.1038/s41586-019-1007-8. 30867590. 1476-4687. 6647838. 2019Natur.567..399R.
  10. News: Cancer's 'internal wiring' predicts relapse risk. Gallagher. James. 2019-03-14. 2019-08-29.
  11. Web site: Breast cancer test could predict chances of disease's return 20 years later, study shows. 2019-03-13. The Independent. 2019-08-29.
  12. News: DNA 'barcode' can transform cancer care. Walsh. Fergus. 2018-06-27. 2019-08-29.
  13. Web site: Breast cancer DNA 'barcoding' programme set to expand. Pilgrim. Tom. 2018-07-23. cambridgenews. 2019-08-29.
  14. Web site: PBCP study takes breast cancer research to the next level in the development of personalised cancer medicine Cambridge University Hospitals. www.cuh.nhs.uk. 2019-08-29.
  15. Web site: Professor Carlos Caldas The Academy of Medical Sciences. acmedsci.ac.uk. 2019-08-29.
  16. Web site: Fellows European Academy of Cancer Sciences. www.europeancanceracademy.eu. 2019-08-29. 2019-07-04. https://web.archive.org/web/20190704091011/https://www.europeancanceracademy.eu/content/directory.php. dead.
  17. Web site: Find people in the EMBO Communities. people.embo.org. 2019-08-29.
  18. Web site: Three Group Leaders elected to EMBO Membership. 2015-05-20. Cancer Research UK Cambridge Institute. 2019-08-29.
  19. Web site: Press Release: ESMO Recognises Carlos Caldas with Hamilton Fairley Award ESMO. www.esmo.org. 2019-08-29.
  20. Web site: ESHG Award ESHG. www.eshg.org. 2021-03-25.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Carlos Caldas".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2025, A B Cryer, All Rights Reserved. Cookie policy.