| Type: | Cardinal |
| Honorific Prefix: | His Eminence |
| Carlo Cristofori | |
| Prefect of the Congregation for Indulgences and Sacred Relics | |
| Church: | Roman Catholic Church |
| Appointed: | 14 March 1889 |
| Term End: | 30 January 1891 |
| Predecessor: | Serafino Vannutelli |
| Successor: | Giuseppe d'Annibale |
| Other Post: | Cardinal-Deacon of Santi Vito, Modesto e Crescenzia (1885-91) |
| Cardinal: | 27 July 1885 |
| Created Cardinal By: | Pope Leo XIII |
| Rank: | Cardinal-Deacon |
| Birth Name: | Carlo Cristofori |
| Birth Date: | 5 January 1813 |
| Birth Place: | Viterbo, Papal States |
| Death Place: | Palazzo Sachetti, Rome, Kingdom of Italy |
| Buried: | Campo Verano |
| Parents: | Luigi Cristofori Anna Riccioli |
| Previous Post: | Prefect of the Vatican Secret Archives (1873-77) |
Carlo Cristofori (5 January 1813 – 30 January 1891) was an Italian Cardinal of the Roman Catholic Church who was Cardinal-Deacon of Santi Vito, Modesto e Crescenzio from 1885 to 1891.