| Type: | Cardinal |
| Honorific-Prefix: | His Eminence |
| Carlo Colonna | |
| Cardinal-Deacon of Sant'Agata de' Goti | |
| Church: | Catholic Church |
| Birth Date: | November 17, 1665 |
| Birth Place: | Rome, Italy |
| Death Date: | July 8, 1739 (age 73) |
Carlo Colonna (November 17, 1665 – July 8, 1739) was a Roman Catholic cardinal.
Carlo Colonna was born on November 17, 1665, in Rome, Italy, the third child of Lorenzo Onofrio Colonna, prince and duke of Paliano, and Maria Mancini, niece of Cardinal Jules Raymond Mazarin.