| Carlisle Littlejohn | |
| Position: | Pitcher |
| Bats: | Right |
| Throws: | Right |
| Birth Date: | October 6, 1901 |
| Birth Place: | Irene, Texas |
| Death Place: | Kansas City, Missouri |
| Debutleague: | MLB |
| Debutdate: | May 11 |
| Debutyear: | 1927 |
| Debutteam: | St. Louis Cardinals |
| Finalleague: | MLB |
| Finaldate: | June 23 |
| Finalyear: | 1928 |
| Finalteam: | St. Louis Cardinals |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 5-2 |
| Stat2label: | Strikeouts |
| Stat2value: | 22 |
| Stat3label: | Earned run average |
| Stat3value: | 4.14 |
| Teams: |
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Charles Carlisle Littlejohn was a professional baseball pitcher. He played parts of two seasons in Major League Baseball, and, for the St. Louis Cardinals.