Carbosulfan Explained

Carbosulfan is an organic compound adherent to the carbamate class. At normal conditions, it is brown viscous liquid. It is not very stable; it decomposes slowly at room temperature. Its solubility in water is low but it is miscible with xylene, hexane, chloroform, dichloromethane, methanol and acetone. Carbosulfan is used as an insecticide.[1] The European Union banned use of carbosulfan in 2007.[2]

Its oral LD50 for rats is 90 to 250 mg/kg bw, inhalation LC50 is 0.61 mg/L. Carbosulfan is only slightly absorbed through skin (LD50 >2000 mg/kg for rabbits). The mechanism of toxicity is based on reversible inhibition of acetylcholinesterase (as for carbamates generally).[3] Carbosulfan has very low maximum residue limits for use in the EU and UK examples of this can be seen in apples and oranges, where it is 0.05 mg/kg.

See also

References

  1. http://www.inchem.org/documents/jmpr/jmpmono/v84pr47.htm CARBOSULFAN – Pesticide residues in food – 1984
  2. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2007:156:0028:0029:EN:PDF COMMISSION DECISION of 13 June 2007 concerning the non-inclusion of carbosulfan in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing that substance
  3. http://www.inchem.org/documents/jmpr/jmpmono/v2003pr02.htm CARBOSULFAN – Pesticide residues in food – 2003