Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone explained

Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone (FCCP) is an ionophore that is a mobile ion carrier. It is referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through the mitochondrial membrane before they can be used to provide the energy for oxidative phosphorylation.[1] It is a nitrile and hydrazone. FCCP was first described in 1962 by Heytler.[2]

See also

Notes and References

  1. https://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?mode=&term=FCCP MeSH Descriptor Data
  2. Heytler, P G . A new class of uncoupling agents — Carbonyl cyanide phenylhydrazones . Biochemical and Biophysical Research Communications . 7 . 4 . 272–275 . 1962 . 10.1016/0006-291X(62)90189-4. 13907155 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.