Carbestrol Explained

Carbestrol (developmental code names NSC-19962, ORF-2166) is a synthetic, nonsteroidal estrogen of the cyclohexenecarboxylic acid group and seco analogue of doisynolic acid that was described in the literature in 1956 and developed for the treatment of prostate cancer in the 1960s but was never marketed.^{[1] [2] [3] [4]}

See also

• Fenestrel
• Methallenestril
• Doisynoestrol
• Bisdehydrodoisynolic acid

Notes and References

1. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 516–.
2. Arduino LJ . Carbestrol (NSC-19962) Treatment of Patients with Prostatic Carcinoma-Preliminary Report . Cancer Chemotherapy Reports . 39 . 67–75 . July 1964 . 14201278 .
3. Kogler J, Hill G, Sedransk N, Cole DR, Weiss AJ, Wilson W . Phase II study of carbestrol (NSC-19962) in patients with solid tumors . Cancer Chemotherapy Reports . 56 . 5 . 641–647 . October 1972 . 4652590 .
4. Book: Kirk RE, Othmer DF . Encyclopedia of chemical technology. 1980. Wiley. 978-0-471-02065-3. 672.