Caprine alphaherpesvirus 1 explained

Caprine alphaherpesvirus 1 (CpHV-1) is a species of virus known to infect goats worldwide. It has been shown to produce systemic and respiratory symptoms in kids and to cause abortions in adult goats.[1]

The virus is in the genus Varicellovirus, subfamily Alphaherpesvirinae, family Herpesviridae, and order Herpesvirales.[2]

It is less studied than some of the other ruminant viruses in the genus Varicellovirus including Bovine alphaherpesvirus 1 (BoHV-1), and research conflicts about its level of species specificity and its ability to cause bovine infection and illness.[3] [4]   Like many other members of its genus, CpHV-1 has been shown to replicate in the respiratory tract and to cause latent infections.  There is not currently a vaccine.[5]

Notes and References

  1. Martins. Bruno. Ebling. Rafael C.. Martins. Mathias. Diel. Diego G.. Weiblen. Rudi. Flores. Eduardo F.. 2019-11-01. Antigenic relationships between Caprine alphaherpesvirus 1 (CpHV-1) and Bovine alphaherpesvirus 1 (BoHV-1) and experimental CpHV-1 infection of kids and calves. Microbial Pathogenesis. en. 136. 103663. 10.1016/j.micpath.2019.103663. 31404631. 0882-4010. free.
  2. Web site: ICTV Master Species List 2018b.v2. International Committee on Taxonomy of Viruses (ICTV). 19 June 2019.
  3. Azab. Walid. Dayaram. Anisha. Greenwood. Alex D.. Osterrieder. Nikolaus. 2018-09-28. How Host Specific Are Herpesviruses? Lessons from Herpesviruses Infecting Wild and Endangered Mammals. Annual Review of Virology. 5. 1. 53–68. 10.1146/annurev-virology-092917-043227. 30052491. 51726438. 2327-056X. free.
  4. Thiry. Julien. Keuser. Véronique. Muylkens. Benoît. Meurens. François. Gogev. Sacha. Vanderplasschen. Alain. Thiry. Etienne. March 2006. Ruminant alphaherpesviruses related to bovine herpesvirus 1. Veterinary Research. 37. 2. 169–190. 10.1051/vetres:2005052. 16472518. 0928-4249. free.
  5. Web site: Vaccines. 2020-06-09. www.mdpi.com. en.