Capravirine Explained

Capravirine was a non-nucleoside reverse transcriptase inhibitor which reached phase II trials before development was discontinued by Pfizer.^{[1] [2]} Both phase IIb trials which were conducted failed to demonstrate that therapy with capravirine provided any significant advantage over existing triple-drug HIV therapies, and pharmacology studies showed that capravirine may interact with other HIV drugs.^{[3] [4]}

References

1. Web site: Capravirine. PubChem. pubchem.ncbi.nlm.nih.gov. en. 2019-06-02.
2. Web site: Capravirine - Anti-Retroviral Drug. Drug Development Technology. en-GB. 2019-06-02.
3. Web site: Capravirine - Anti-Retroviral Drug. Drug Development Technology. en-GB. 2019-06-02.
4. A Study of Capravirine Plus VIRACEPT Plus Two Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected Patients Who Failed Previous Anti-HIV Treatments - Full Text View - ClinicalTrials.gov. clinicaltrials.gov. 23 June 2005 . en. 2019-06-02.