| Campofranco | |
| Official Name: | Comune di Campofranco |
| Coordinates: | 37.5167°N 55°W |
| Region: | Sicily |
| Province: | Caltanissetta (CL) |
| Mayor: | Rosario Pitanza |
| Area Total Km2: | 83.97 |
| Population Total: | 3032 |
| Population As Of: | 30 April 2017 |
| Population Footnotes: | [1] |
| Population Demonym: | Campofranchesi |
| Elevation M: | 350 |
| Saint: | Saint Calogerus |
| Postal Code: | 93010 |
| Area Code: | 0934 |
Campofranco (Campufrancu in Sicilian) is a comune (municipality) in the Province of Caltanissetta in the Italian region Sicily, located about 70km (40miles) southeast of Palermo and about 35km (22miles) west of Caltanissetta.
Campofranco borders the following municipalities: Aragona, Casteltermini, Grotte, Milena, Sutera.