| Calpulalpan | |
| Pushpin Map: | Mexico Tlaxcala#Mexico |
| Pushpin Label Position: | above |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Tlaxcala |
| Subdivision Type2: | Municipal seat |
| Subdivision Name2: | Calpulalpan |
| Population As Of: | 2005 |
| Timezone: | Central |
| Utc Offset: | -6 |
| Coordinates: | 19.5833°N -98.5667°W |
Calpulalpan is a municipality in the Mexican state of Tlaxcala.[1] The area of the municipality is 254.82 km².
The municipal seat is at Calpulalpan.