Calfactant Explained

Calfactant, also known as Infasurf,[1] is an intratracheal suspension derived from the natural surfactant in calf lungs. It is used in premature infants with lung surfactant deficiency that causes infant respiratory distress syndrome (IRDS).[2]

Mechanism of action

Lung surfactant is essential for effective ventilation as it modifies alveolar surface tension.[3] IRDS is caused by a lung surfactant deficiency. Calfactant serves as a substitute for the natural surfactant.

Notes and References

  1. Web site: Infasurf . 2011-12-16 . https://web.archive.org/web/20111209035824/http://www.infasurf.com/home# . 2011-12-09 . dead .
  2. Drugs.com: Web site: Calfactant . Drugs.com .
  3. Schurch S, Lee M, Gehr P . 97007574 . 10.1351/pac199264111745 . Pulmonary surfactant: Surface properties and function of alveolar and airway surfactant . Pure and Applied Chemistry . 64 . 11 . 1745–1750 . 1992 . free .

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