| Official Name: | Cairo, Oregon |
| Settlement Type: | Unincorporated community |
| Postal Code Type: | ZIP Code |
| Pushpin Map: | USA Oregon#USA |
| Pushpin Map Caption: | Location within the state of Oregon##Location within the USA |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Oregon |
| Subdivision Type2: | County |
| Subdivision Name2: | Malheur |
| Timezone: | Mountain |
| Utc Offset: | -7 |
| Timezone Dst: | Mountain |
| Utc Offset Dst: | -6 |
| Area Code: | 541 |
| Coordinates: | 43.9961°N -117.0092°W |
| Elevation Ft: | 2192 |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 1118451[1] |
| Footnotes: | Coordinates and elevation from Geographic Names Information System |
Cairo is an unincorporated community in Malheur County, Oregon, United States.[1] Its elevation is 2192feet above sea level.[1] It is about 4miles southwest of Ontario and a half mile north of Cairo Junction, where U.S. Route 20 and U.S. Route 26, running concurrently with Oregon Route 201, turn south towards Nyssa.[2] Route 201 also continues north from Cairo Junction through Cairo and towards Ontario.[2]
Cairo was a station on the Oregon Short Line Railroad (OSL) to Vale.[3] The OSL line is now part of the Union Pacific mainline. Cairo Elementary School in Cairo Junction is part of the Ontario School District; the school was built in 1957.[4]