Caetano Reis e Sousa explained

Caetano Reis e Sousa
Birth Name:Caetano Maria Pacheco Pais dos Reis e Sousa
Birth Place:Lisbon, Portugal
Fields:Immunology
Workplaces:Francis Crick Institute
Imperial College London
Imperial Cancer Research Fund
National Institute of Allergy and Infectious Diseases
Education:Atlantic College
Alma Mater:Imperial College London (BSc)
University of Oxford (DPhil)
Thesis Title:Phagocytosis of antigens by Langerhans cells
Thesis Url:https://ora.ox.ac.uk/objects/uuid:1f69e0f0-1d08-4c2f-aa02-216231100f14
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Doctoral Advisor:Jonathan Austyn
Awards:EMBO Member (2006)[1]
Louis-Jeantet Prize for Medicine (2017)
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Caetano Maria Pacheco Pais dos Reis e Sousa (born 1968) is a senior group leader at the Francis Crick Institute[2] [3] [4] and a professor of Immunology at Imperial College London.

Education

Reis e Sousa was educated at Atlantic College in Wales,[4] Imperial College London (BSc) and the University of Oxford where he was awarded a Doctor of Philosophy degree in 1992 for research on dendritic cells, and the phagocytosis of antigens by Langerhans cells supervised by Jonathan Austyn.[5]

Career and research

After working as a postdoctoral researcher at the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, with Ronald Germain, he joined the Imperial Cancer Research Fund (ICRF) in 1998. He headed the Immunobiology Laboratory which became part of the Francis Crick Institute in 2015. He is also a professor of Immunology at Imperial College London[6] and honorary professor at University College London (UCL) and King's College London.[7]

Caetano's research centres on the mechanisms involved in sensing infection, cancer and tissue injury.[7] He has helped to define the cells and pathways involved in innate immune detection of RNA viruses, fungi and dead cells.[7] [8] [9] [10]

Awards and honours

Reis e Sousa was elected a Fellow of the Royal Society (FRS) in 2019, and is also a Fellow of the Academy of Medical Sciences (FMedSci), a member of the European Molecular Biology Organization (EMBO)[1] and was made an Officer of the Order of Sant'Iago da Espada by the Government of Portugal in 2009.[7] He was awarded the Louis-Jeantet Prize for Medicine in 2017.[11]

Notes and References

  1. Web site: Caetano Reis e Sousa. people.embo.org. European Molecular Biology Organization. 2006. Anon.
  2. Web site: Caetano Reis e Sousa: Immunobiology Laboratory. crick.ac.uk.
  3. Web site: Researchers: Caetano Reis e Sousa. crick.ac.uk.
  4. Bashyam. Hema. Caetano Reis e Sousa: harnessing DC power. The Journal of Experimental Medicine. 205. 9. 2008. 1946–1947. 0022-1007. 10.1084/jem.2059pi. 18762569 . 2526189 .
  5. DPhil. Phagocytosis of antigens by Langerhans cells. Caetano Maria Pacheco Pais dos. Reis e Sousa. 1992. . University of Oxford. 863542179.
  6. Web site: Professor Caetano Reis e Sousa. Imperial College London.
  7. Web site: royalsociety.org. Anon. https://web.archive.org/web/20190424061730/https://royalsociety.org/people/caetano-reis-e-sousa-14117/. 24 April 2019. Professor Caetano Reis e Sousa FMedSci FRS. Royal Society. London. 2019. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
  8. Diebold. S. S.. Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA. Science. 303. 5663. 2004. 1529–1531. 0036-8075. 10.1126/science.1093616. 14976261. 2004Sci...303.1529D. 33144196. free.
  9. Kato. Hiroki. Takeuchi. Osamu. Sato. Shintaro. Yoneyama. Mitsutoshi. Yamamoto. Masahiro. Matsui. Kosuke. Uematsu. Satoshi. Jung. Andreas. Kawai. Taro. Ishii. Ken J.. Yamaguchi. Osamu. Otsu. Kinya. Tsujimura. Tohru. Koh. Chang-Sung. Reis e Sousa. Caetano. Matsuura. Yoshiharu. Fujita. Takashi. Akira. Shizuo. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature. 441. 7089. 2006. 101–105. 0028-0836. 10.1038/nature04734. 16625202. 2006Natur.441..101K. 2270879.
  10. Pichlmair. A.. Schulz. O.. Tan. C. P.. Naslund. T. I.. Liljestrom. P.. Weber. F.. Reis e Sousa. C.. RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates. Science. 314. 5801. 2006. 997–1001. 0036-8075. 10.1126/science.1132998. 17038589. 2006Sci...314..997P. 44366096. free.
  11. Web site: Caetano REIS E SOUSA . jeantet.ch. 4 October 2017.