Cadila Pharmaceuticals Explained

Cadila Pharmaceuticals should not be confused with Cadila Healthcare.

Cadila Pharmaceuticals Limited
Logo Alt:Cadila_Pharmaceuticals_Logo
Type:Private
Foundation:1951
Founder:Indravadan Modi
Location City:Ahmedabad, Gujarat
Num Employees:8,000
Subsid:IRM Ltd
Location Country:India
Key People:Rajiv Modi
(Chairman and Managing Director)
Industry:Pharmaceuticals
Products:APIs, generic drugs
Revenue: (FY23)
Net Income: (FY23)[1]

Cadila Pharmaceuticals is an Indian multinational pharmaceutical company based in Ahmedabad. The company's operations focus on manufacturing products ranging from active pharmaceutical intermediates, finished formulations, food supplements, biotechnology products and pharmaceutical machinery.[2]

History

Cadila Laboratories

In 1951 Indravadan A Modi had quit his job as a chemist in a Mumbai firm to start Cadila Laboratories with childhood friend Ramanbhai Patel. The company started in a rented bungalow with a capital of Rs 25,000 and achieved a turnover of around Rs 1.25 lakh in its first year of operation.[3]

1995: Birth of Cadila Pharmaceuticals

The Modi and Patel families decided to split the business in 1995, two entities were formed - Cadila Pharmaceuticals Ltd (owned and controlled by Indravadan Modi and his son Rajiv Modi) and Cadila Healthcare (owned by Ramanbhai Patel and his son Pankaj Patel family).[3]

Operations

Cadila Pharmaceuticals has its formulation manufacturing facilities at Dholka, Gujarat (India); Samba, Jammu (India) and at Addis Ababa (Ethiopia) and 2 API manufacturing facilities are located at Ankleshwar, Gujarat. The manufacturing facility at Dholka and the API unit at Ankleshwar in Gujarat are USFDA-certified; the overseas manufacturing facility at Ethiopia is the WHO - cGMP compliant facility.[4]

Research

Cadila Pharmaceuticals has established a dedicated R&D facility, spread over 1,05,000 sq. ft. area at Dholka, Gujarat, India which is staffed by 300 scientists.

The company has five IND dossiers filed with the USFDA for pulmonary tuberculosis, lung cancer, prostate cancer, bladder cancer and melanoma. The company has submitted ten ANDAs.[5]

Products and services

The Samba plant specializes in the production of a wide variety of drugs, totaling 140 types.It was commissioned in September 2002, showcasing Cadila Pharmaceuticals' commitment to expanding its manufacturing capabilities.With an expansive area of 11 acres, the plant represents a significant investment in pharmaceutical manufacturing infrastructure in the region.The project type being derivative indicates a focus on producing pharmaceutical derivatives or derivative-based products.The total budget for the project is 100 crores.The project was expected to be complete within around 800 days from the date of commencement.Cadila Pharmaceuticals is the only Indian manufacturer of natural Streptokinase and Hyaluronic Acid products. The company was also the first in the world to introduce Rabeprazole in IV form – 'Rabeloc'.[6] In 2009, the world's first boosted-Rifampicin fixed-dose combination for the treatment of Tuberculosis – 'Risorine'[7] and world's first drug combination for prevention of Cardiovascular Diseases – 'Polycap' were introduced by Cadila Pharmaceuticals.[8] For the patients with Non Small Cell Lung Cancer (NSCLC), the company introduced 'Mycidac-C' - first in the class active immunotherapy as well as drug targeting Desmocollin.[9] Some of the top brands of the company are Aciloc, Envas, Calcirol, Haem Up, Vasograin, Tricort, Fludac, Rabiloc, Trigan-D, Mycobutol and Sepsivac.

On March 4, 2024, Cadila Pharmaceuticals announced the launch of Cadiflu Tetra, a quadrivalent influenza vaccine approved for use in adults and children by the Drugs Controller General of India (DCGI), using proprietary technology with nano-sized particles to mimic the virus's external structure without containing its genetic material.[10]

Alliances

In 2019, Cadila Pharmaceuticals formed a partnership with Norwegian start-up, Serca Pharmaceuticals to develop new treatment for heart patients.[11]

Controversies

Company

In 2014, a cautionary notice appeared on the FDA website highlighting substantial manufacturing practice discrepancies discovered by inspectors in March at Cadila Pharmaceuticals' Ankleshwar facility in Gujarat.[12] This incident marked one among several Indian pharmaceutical companies receiving regulatory warnings from the FDA, indicating increased scrutiny on generic drugmakers.[13] A similar kind of notices were again issued in 2016[14] and 2019.[15]

Management

In 2018, the chairman of the company, Rajiv Modi, went through a widely publicized and contentious divorce with his wife, Monica, who comes from a prominent Mumbai-based business family of Garware. At that time, Modi transferred to Monica, who relinquished her rights, while custody of their son was awarded to Modi.[16] [17]

In December 2023, Gujarat Police complied with a Gujarat High Court order, initiating a case against Rajiv Modi.[18] The case involves accusations of rape, assault, and intentional insult by a Bulgarian woman employed as a flight attendant and personal assistant at the company. She reported multiple instances of sexual harassment from February to March 2023, stating that she was terminated in April 2023 after resisting Modi's alleged “illicit demands”.[19] [20]

External links

Notes and References

  1. Web site: Cadila Pharmaceuticals Limited . Crediwatch . 18 December 2023. registration.
  2. Web site: Bureau . BL Ahmedabad . Cadila Pharma to expand and upgrade its existing facilities in Gujarat . BusinessLine . 2023-03-22 . 2023-09-11.
  3. Web site: Carrying the legacy forward: Rajiv Modi. Sohini. Das. 28 January 2014. Business Standard.
  4. http://pharma.financialexpress.com/sections/management/1698-caring-cadila Financial Express 28 January 2013
  5. Web site: Welcome to India in Business. www.indiainbusiness.nic.in. 24 March 2014. https://web.archive.org/web/20140707164613/http://www.indiainbusiness.nic.in/economy/pharma.htm. 7 July 2014. dead.
  6. Web site: Cadila Pharma unveils acidity drug in IV form. Our Regional. Bureau. 16 July 2004. Business Standard.
  7. Web site: Cadila launches new drug for TB treatment. 31 October 2009. dna.
  8. Web site: Cadila Pharmaceuticals launches Polycap, which reduces cardiovascular and stroke risk substantially. 2 April 2009. The Financial Express.
  9. Web site: Economic Times 21 November 2013.
  10. Web site: Bureau . BL Ahmedabad . 2024-03-04 . Cadila Pharmaceuticals launches advanced Quadrivalent Influenza Vaccine . 2024-03-04 . BusinessLine . en.
  11. Web site: Cadila Pharma inks pact with Norwegian start-up to develop new treatment for heart patients. @businessline. 10 January 2019 . en. 2019-01-11.
  12. News: Mishra . Digbijay . Das . Sohini . 13 November 2014 . US FDA scolds Cadila Pharma over manufacturing practice in Gujrat plant . 6 January 2024.
  13. News: 12 November 2014 . FDA warns Cadila Pharma over drug production processes . 6 January 2023 . Reuters.
  14. News: RAJAGOPAL . DIVYA . 2016-01-01 . Cadila gets US FDA warning for violating standards at Moraiya and Ahmedabad plants . 2024-01-06 . The Economic Times . 0013-0389.
  15. Web site: Research . Center for Drug Evaluation and . 2022-11-28 . Cadila Healthcare Limited - 584856 - 10/29/2019 . 2024-01-06 . Center for Drug Evaluation and Research . en.
  16. News: 2018-10-31 . Gujarat: Cadila Pharma owner pays wife Rs 200 crore . 2024-01-06 . The Times of India . 0971-8257.
  17. Web site: Cadila Pharmaceuticals boss Rajiv Modi swallows a Rs 200-cr divorce pill . 2024-01-06 . DNA India . en.
  18. Web site: Khatri . Dhananjay . 2023-12-24 . Gujarat HC orders probe against Cadila Pharma CMD into rape allegations . 2024-01-06 . CNBCTV18 . en.
  19. Web site: 2023-12-31 . Cops register FIR against Cadila CMD for rape of Bulgarian woman after Gujarat HC order . 2024-01-06 . The Indian Express . en.
  20. Web site: PTI . Gujarat police register rape case against Cadila Pharma CMD after HC order . 2024-01-06 . Deccan Herald . en.