CYP6M2 explained
| Organism: | Anopheles gambiae |
| Taxid: | 7165 |
| Cytochrome P450 6m2 |
| Symbol: | Cyp6m2 |
| Ecnumber: | 1.14.-.- |
| Entrezgene: | 5668319 |
CYP6M2 is a gene location in Anopheles gambiae chromosome 3R, involved in the insecticide resistant.[1] The enzyme encoded by this gene is capable of directly metabolizing pyrethroids,[2] belongs to the cytochrome P450 family CYP6[3]
Notes and References
- Djouaka . RF . Bakare . AA . Coulibaly . ON . Akogbeto . MC . Ranson . H . Hemingway . J . Strode . C . Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria. . BMC Genomics . 13 November 2008 . 9 . 538 . 10.1186/1471-2164-9-538 . 19014539. 2588609 . free .
- Ismail HM, O'Neill PM, Hong DW, Finn RD, Henderson CJ, Wright AT, Cravatt BF, Hemingway J, Paine MJ . 6 . Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions . Proceedings of the National Academy of Sciences of the United States of America . 110 . 49 . 19766–71 . December 2013 . 24248381 . 3856776 . 10.1073/pnas.1320185110 . 2013PNAS..11019766I . free .
- Wagah . MG . Korlević . P . Clarkson . C . Miles . A . Anopheles gambiae 1000 Genomes . Consortium. . Lawniczak . MKN . Makunin . A . Genetic variation at the Cyp6m2 putative insecticide resistance locus in Anopheles gambiae and Anopheles coluzzii. . Malaria Journal . 25 May 2021 . 20 . 1 . 234 . 10.1186/s12936-021-03757-4 . 34034756. 8146665 . free .
