CYP6G1 explained
| Organism: | Drosophila melanogaster |
| Taxid: | 7227 |
| Cytochrome P450 6g1 |
| Symbol: | Cyp6g1 |
| Altsymbols: | CYP6-like, DDT-R, Rst(2)DDT |
| Refseqmrna: | NM_136899.4 |
| Refseqprotein: | NP_610743.2 |
| Uniprot: | Q9V674 |
| Ecnumber: | 1.14.-.- |
| Entrezgene: | 36316 |
| Homologene: | 59722 |
| Chromosome: | 2R |
| Entrezchromosome: | NT_033778.4 |
| Genloc Start: | 12185251 |
| Genloc End: | 12188845 |
Cyp6g1 or DDT-R is an insecticide resistance gene for resistance to DDT in Drosophila melanogaster.[1] It belongs to the cytochrome P450 family and is located in chromosome 2R.[2] Following up their earlier work, Daborn et al. 2002 find the DDT-R gene induces overtranscription of Cyp6g1, of which there are 4 duplicates.[3] They also find several substrates of Cyp6g1, namely DDT, lufenuron, and nitenpyram.
External links
Notes and References
- McCart C, ffrench-Constant RH . Dissecting the insecticide-resistance- associated cytochrome P450 gene Cyp6g1 . Pest Management Science . 64 . 6 . 639–645 . June 2008 . 18338338 . 10.1002/ps.1567 . Richard ffrench-Constant . free .
- Le Goff G, Hilliou F . Resistance evolution in Drosophila: the case of CYP6G1 . Pest Management Science . 73 . 3 . 493–499 . March 2017 . 27787942 . 10.1002/ps.4470 .
- Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B, Aguade M, Akashi H, Anderson WW, Aquadro CF, Ardell DH, Arguello R, Artieri CG, Barbash DA, Barker D, Barsanti P, Batterham P, Batzoglou S, Begun D, etal . 6 . Andrew G. Clark . Michael Eisen . Drosophila 12 Genomes Consortium . Evolution of genes and genomes on the Drosophila phylogeny . Nature . 450 . 7167 . 203–218 . November 2007 . 17994087 . 10.1038/nature06341 . . 2007Natur.450..203C . 2416812 . free .
