CYP18 family explained

Cytochrome P450, family 18, also known as CYP18, is an animal cytochrome P450 family found in insect genomes.[1] It is involved in insecticide resistance.[2] The first member gene identified was CYP18A1, from a Drosophila melanogaster fly, acting as a dimethylnitrosamine demethylase.[3]

Notes and References

  1. Nelson . DR . Metazoan cytochrome P450 evolution. . Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology . November 1998 . 121 . 1–3 . 15–22 . 10.1016/s0742-8413(98)10027-0 . 9972448.
  2. Jin . Y . Gao . Y . Zhang . H . Wang . L . Yang . K . Dong . H . Detoxification enzymes associated with butene-fipronil resistance in Epacromius coerulipes. . Pest Management Science . January 2020 . 76 . 1 . 227–235 . 10.1002/ps.5500 . 31150148. 171093218 . free .
  3. Bassett . MH . McCarthy . JL . Waterman . MR . Sliter . TJ . Sequence and developmental expression of Cyp18, a member of a new cytochrome P450 family from Drosophila. . Molecular and Cellular Endocrinology . 4 July 1997 . 131 . 1 . 39–49 . 10.1016/s0303-7207(97)00093-2 . 9256362. 38929634 .

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