CYP15 family explained

Cytochrome P450, family 15, also known as CYP15, is an animal cytochrome P450 family found in insect genome,[1] involved in juvenile hormone biosynthesis.[2] The first gene identified in this family is the DpCYP15A1 from the Diploptera punctata (Pacific beetle cockroach), encodes an epoxidase of methyl farnesoate, a precursor of juvenile hormone, alone with its ortholog TcCYP15A1 in Tribolium castaneum (red flour beetle).[3]

Notes and References

  1. Nelson . DR . Metazoan cytochrome P450 evolution. . Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology . November 1998 . 121 . 1–3 . 15–22 . 10.1016/s0742-8413(98)10027-0 . 9972448.
  2. Daimon . T . Shinoda . T . Function, diversity, and application of insect juvenile hormone epoxidases (CYP15). . Biotechnology and Applied Biochemistry . January 2013 . 60 . 1 . 82–91 . 10.1002/bab.1058 . 23586995. 25181420 .
  3. Minakuchi . C . Ishii . F . Washidu . Y . Ichikawa . A . Tanaka . T . Miura . K . Shinoda . T . Expressional and functional analysis of CYP15A1, a juvenile hormone epoxidase, in the red flour beetle Tribolium castaneum. . Journal of Insect Physiology . September 2015 . 80 . 61–70 . 10.1016/j.jinsphys.2015.04.008 . 25921675.

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