CXCL6 explained

chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
Hgncid:	10643
Symbol:	CXCL6
Altsymbols:	SCYB6, GCP-2, CKA-3
Entrezgene:	6372
Omim:	138965
Refseq:	NM_002993
Uniprot:	P80162
Chromosome:	4
Arm:	q
Band:	21

Chemokine (C-X-C motif) ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family that is also known as granulocyte chemotactic protein 2 (GCP-2). As its former name suggests, CXCL6 is a chemoattractant for neutrophilic granulocytes.^{[1] [2]} It elicits its chemotactic effects by interacting with the chemokine receptors CXCR1 and CXCR2.^[2] The gene for CXCL6 is located on human chromosome 4 in a cluster with other CXC chemokine genes.^{[3] [4]}

References

1. Proost P, Wuyts A, Conings R, Lenaerts J, Billiau A, Opdenakker G, Van Damme J . Human and bovine granulocyte chemotactic protein-2: complete amino acid sequence and functional characterization as chemokines . Biochemistry . 32 . 38 . 10170–7 . 1993 . 8399143 . 10.1021/bi00089a037.
2. Wuyts A, Van Osselaer N, Haelens A, Samson I, Herdewijn P, Ben-Baruch A, Oppenheim J, Proost P, Van Damme J . Characterization of synthetic human granulocyte chemotactic protein 2: usage of chemokine receptors CXCR1 and CXCR2 and in vivo inflammatory properties . Biochemistry . 36 . 9 . 2716–23 . 1997 . 9054580 . 10.1021/bi961999z.
3. Modi W, Chen Z . Localization of the human CXC chemokine subfamily on the long arm of chromosome 4 using radiation hybrids . Genomics . 47 . 1 . 136–9 . 1998 . 9465307 . 10.1006/geno.1997.5100.
4. O'Donovan N, Galvin M, Morgan J . Physical mapping of the CXC chemokine locus on human chromosome 4 . Cytogenet Cell Genet . 84 . 1–2 . 39–42 . 1999 . 10343098 . 10.1159/000015209. 8087808 .