5F-CUMYL-P7AICA explained

5F-CUMYL-P7AICA (also known as CUMYL-5F-P7AICA or SGT-263) is a pyrrolo[2,3-b]pyridine-3-carboxamide based synthetic cannabinoid that has been sold as a designer drug.[1] [2] [3] [4] [5] [6] It was first identified by the EMCDDA in February 2015.[7]

See also

Notes and References

  1. Ernst L, Brandhorst K, Papke U, Altrogge A, Zodel S, Langer N, Beuerle T . Identification and quantification of synthetic cannabinoids in 'spice-like' herbal mixtures: Update of the German situation in early 2017 . Forensic Science International . 277 . 51–58 . August 2017 . 28601726 . 10.1016/j.forsciint.2017.05.019 .
  2. Staeheli SN, Poetzsch M, Veloso VP, Bovens M, Bissig C, Steuer AE, Kraemer T . In vitro metabolism of the synthetic cannabinoids CUMYL-PINACA, 5F-CUMYL-PINACA, CUMYL-4CN-BINACA, 5F-CUMYL-P7AICA and CUMYL-4CN-B7AICA . Drug Testing and Analysis . 10 . 1 . 148–157 . January 2018 . 28885775 . 10.1002/dta.2298 .
  3. Bovens M, Bissig C, Staeheli SN, Poetzsch M, Pfeiffer B, Kraemer T . Structural characterization of the new synthetic cannabinoids CUMYL-PINACA, 5F-CUMYL-PINACA, CUMYL-4CN-BINACA, 5F-CUMYL-P7AICA and CUMYL-4CN-B7AICA . Forensic Science International . 281 . 98–105 . December 2017 . 29125990 . 10.1016/j.forsciint.2017.10.020 .
  4. Banister SD, Adams A, Kevin RC, Macdonald C, Glass M, Boyd R, Connor M, McGregor IS, Havel CM, Bright SJ, Ventura Vilamala M, Gil Lladanosa C, Barratt MJ, Gerona RR . Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold-hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA . Drug Testing and Analysis . 11 . 2 . 279–291 . August 2018 . 30151911. 10.1002/dta.2491 . 52100276 . 1959.4/unsworks_58933 . free .
  5. Walle N, Nordmeier F, Doerr AA, Peters B, Laschke MW, Menger MD, Schmidt PH, Meyer MR, Schaefer N . Comparison of in vitro and in vivo models for the elucidation of metabolic patterns of 7-azaindole-derived synthetic cannabinoids exemplified using cumyl-5F-P7AICA . Drug Testing and Analysis . 13. 1. 74–90. July 2020 . 32678962 . 10.1002/dta.2899 . free .
  6. Gatch MB, Tourigny A, Shetty RA, Forster MJ . Behavioral pharmacology of five novel synthetic cannabinoids . Behavioural Pharmacology . 33. 2&3. 175–183. February 2021 . 33595956 . 10.1097/FBP.0000000000000618 . 8364570 .
  7. Web site: Annual Report on the implementation of Council Decision 2005/387/JHA . Europol . 2015 .
  8. Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL-CBMICA, ADB-BINACA, APP-BINACA, 4F-MDMB-BINACA, MDMB-4en-PINACA, A-CHMINACA, 5F-AB-P7AICA, 5F-MDMB-P7AICA, and 5F-AP7AICA. Cannaert A, Sparkes E, Pike E, Luo JL, Fang A, Kevin RC, Ellison R, Gerona R, Banister SD, Stove CP. ACS Chemical Neuroscience. 2020. 11. 24. 4434–4446. 10.1021/acschemneuro.0c00644. 33253529. 227246346.

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