CTP-dependent riboflavin kinase explained

CTP-dependent riboflavin kinase
Ec Number:2.7.1.161

CTP-dependent riboflavin kinase (Methanocaldococcus jannaschii Mj0056, Mj0056) is an enzyme with systematic name CTP:riboflavin 5′-phosphotransferase.[1] This enzyme catalyses the following chemical reaction

CTP + riboflavin

\rightleftharpoons

CDP + FMN

This archaeal enzyme uses CTP as the donor nucleotide.

Notes and References

  1. Ammelburg M, Hartmann MD, Djuranovic S, Alva V, Koretke KK, Martin J, Sauer G, Truffault V, Zeth K, Lupas AN, Coles M . A CTP-dependent archaeal riboflavin kinase forms a bridge in the evolution of cradle-loop barrels . Structure . 15 . 12 . 1577–90 . December 2007 . 18073108 . 10.1016/j.str.2007.09.027 . free .