CTNNAL1 explained

Alpha-catulin is a protein that in humans is encoded by the CTNNAL1 gene.^{[1] [2]}

Interactions

CTNNAL1 has been shown to interact with AKAP13.^[3]

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Janssens B, Staes K, van Roy F . Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing . Biochim. Biophys. Acta . 1447 . 2–3 . 341–7 . 1999 . 10542337 . 10.1016/s0167-4781(99)00170-0 .
• Demacio PC, Ray PN . Alpha-catulin maps to the familial dysautonomia region on 9q31 . Genome . 44 . 6 . 990–4 . 2002 . 11768226 . 10.1139/gen-44-6-990 .
• Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D . Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation . J. Biol. Chem. . 277 . 47 . 45361–70 . 2003 . 12270917 . 10.1074/jbc.M202447200 . free .
• Shieh YS, Chang LC, Chiu KC, Wu CW, Lee HS . Cadherin and catenin expression in mucoepidermoid carcinoma: correlation with histopathologic grade, clinical stage, and patient outcome . J. Oral Pathol. Med. . 32 . 5 . 297–304 . 2003 . 12694354 . 10.1034/j.1600-0714.2003.00144.x .
• Surpili MJ, Delben TM, Kobarg J . Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1 . Biochemistry . 42 . 51 . 15369–76 . 2004 . 14690447 . 10.1021/bi034575v .
• Merdek KD, Nguyen NT, Toksoz D . Distinct Activities of the α-Catenin Family, α-Catulin and α-Catenin, on β-Catenin-Mediated Signaling . Mol. Cell. Biol. . 24 . 6 . 2410–22 . 2004 . 14993280 . 355851 . 10.1128/mcb.24.6.2410-2422.2004 .

Notes and References

1. Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI . Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin . Genomics . 54 . 1 . 149–54 . Jan 1999 . 9806841 . 10.1006/geno.1998.5458 .
2. Web site: Entrez Gene: CTNNAL1 catenin (cadherin-associated protein), alpha-like 1.
3. Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D . Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation . J. Biol. Chem. . 277 . 47 . 45361–70 . Nov 2002 . 12270917 . 10.1074/jbc.M202447200 . free .