CTDSP1 explained

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 is an enzyme that in humans is encoded by the CTDSP1 gene.^{[1] [2] [3]}

Interactions

CTDSP1 has been shown to interact with SNAI1.^[4]

Further reading

• Marquet S, Lepage P, Hudson TJ, Musser JM, Schurr E . Complete nucleotide sequence and genomic structure of the human NRAMP1 gene region on chromosome region 2q35 . Mammalian Genome . 11 . 9 . 755–62 . September 2000 . 10967134 . 10.1007/s003350010151 . 11308779 .
• Fernandes AO, Campagnoni CW, Kampf K, Feng JM, Handley VW, Schonmann V, Bongarzone ER, Reyes S, Campagnoni AT . 6 . Identification of a protein that interacts with the golli-myelin basic protein and with nuclear LIM interactor in the nervous system . Journal of Neuroscience Research . 75 . 4 . 461–71 . February 2004 . 14743429 . 10.1002/jnr.10882 . 29467544 .
• Yeo M, Lee SK, Lee B, Ruiz EC, Pfaff SL, Gill GN . Small CTD phosphatases function in silencing neuronal gene expression . Science . 307 . 5709 . 596–600 . January 2005 . 15681389 . 10.1126/science.1100801 . 2005Sci...307..596Y . 39722809 .
• Sapkota G, Knockaert M, Alarcón C, Montalvo E, Brivanlou AH, Massagué J . Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways . The Journal of Biological Chemistry . 281 . 52 . 40412–9 . December 2006 . 17085434 . 10.1074/jbc.M610172200 . free .

Notes and References

1. Ma X, Wright J, Dou S, Olsen P, Teeter L, Adams G, Graviss E . Ethnic divergence and linkage disequilibrium of novel SNPs in the human NLI-IF gene: evidence of human origin and lack of association with tuberculosis susceptibility . Journal of Human Genetics . 47 . 3 . 140–5 . Apr 2002 . 11950066 . 10.1007/s100380200016 . free .
2. Yeo M, Lin PS, Dahmus ME, Gill GN . A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5 . The Journal of Biological Chemistry . 278 . 28 . 26078–85 . July 2003 . 12721286 . 10.1074/jbc.M301791200 . free .
3. Web site: Entrez Gene: CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1.
4. Wu Y, Evers BM, Zhou BP . Small C-terminal domain phosphatase enhances snail activity through dephosphorylation . The Journal of Biological Chemistry . 284 . 1 . 640–8 . January 2009 . 19004823 . 2610500 . 10.1074/jbc.M806916200 . free .