Complement receptor of the immunoglobulin family explained

Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells.[1] It is a critical receptor for the phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces.

See also

References

  1. Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M . CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens . Cell . 124 . 5 . 915–27 . 2006 . 16530040 . 10.1016/j.cell.2005.12.039. free .

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