CRIP1 explained

Cysteine-rich protein 1 is a protein that in humans is encoded by the CRIP1 gene.^{[1] [2]}

Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991).[supplied by OMIM]

Further reading

• Gerhard DS . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–2127 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Ota T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–45 . 2004 . 14702039 . 10.1038/ng1285 . vanc. Suzuki Y . Nishikawa T . 3 . Otsuki . Tetsuji . Sugiyama . Tomoyasu . Irie . Ryotaro . Wakamatsu . Ai . Hayashi . Koji . Sato . Hiroyuki . free .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–16903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Khoo C, Blanchard RK, Sullivan VK, Cousins RJ . Human cysteine-rich intestinal protein: cDNA cloning and expression of recombinant protein and identification in human peripheral blood mononuclear cells . Protein Expr. Purif. . 9 . 3 . 379–387 . 1997 . 9126610 . 10.1006/prep.1996.0709 .
• Khoo C, Cousins RJ . Purification and properties of rat cysteine-rich intestinal protein . Biochem. J. . 299 . 2. 445–50 . 1994 . 10.1042/bj2990445 . 8172605 . 1138292 .
• Tsui SK, Yam NY, Lee CY, Waye MM . Isolation and characterization of a cDNA that codes for a LIM-containing protein which is developmentally regulated in heart . Biochem. Biophys. Res. Commun. . 205 . 1 . 497–505 . 1995 . 7999070 . 10.1006/bbrc.1994.2693 .
• Hempe JM, Cousins RJ . Cysteine-rich intestinal protein binds zinc during transmucosal zinc transport . Proc. Natl. Acad. Sci. U.S.A. . 88 . 21 . 9671–9674 . 1991 . 1946385 . 10.1073/pnas.88.21.9671 . 52780 . 1991PNAS...88.9671H . free .

Notes and References

1. Garcia-Barcelo M, Tsui SK, Chim SS, Fung KP, Lee CY, Waye MM . Mapping of the human cysteine-rich intestinal protein gene CRIP1 to the human chromosomal segment 7q11.23 . Genomics . 47 . 3 . 419–422 . Apr 1998 . 9480758 . 10.1006/geno.1997.5134 .
2. Web site: Entrez Gene: CRIP1 cysteine-rich protein 1 (intestinal).