CPD-1 explained
CPD-1 (LS-193743) is a drug with a benzofuranyl piperazine structure, which acts as a potent and selective agonist for the 5-HT2 receptor family, with highest affinity and full agonist efficacy at the 5-HT2C subtype, and lower affinity and partial agonist action at the 5-HT2A and 5-HT2B subtypes.[1] [2]
See also
Notes and References
- Ahmed A, Choo H, Cho YS, Park WK, Pae AN . Identification of novel serotonin 2C receptor ligands by sequential virtual screening . Bioorganic & Medicinal Chemistry . 17 . 13 . 4559–68 . July 2009 . 19464901 . 10.1016/j.bmc.2009.05.003 .
- Rodriguez MM, Overshiner C, Leander JD, Li X, Morrow D, Conway RG, Nelson DL, Briner K, Witkin JM . 6 . Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive-Compulsive Disorder . Frontiers in Psychiatry . 8 . 89 . 2017 . 28588509 . 5438973 . 10.3389/fpsyt.2017.00089 . free .