CP-226,269 explained

CP-226,269 is a drug which acts as a dopamine agonist selective for the D4 subtype, which is used for researching the role of D4 receptors in the brain.[1] [2]

Notes and References

  1. Sharma A, Kramer ML, Wick PF, Liu D, Chari S, Shim S, Tan W, Ouellette D, Nagata M, DuRand CJ, Kotb M, Deth RC . D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia . Molecular Psychiatry . 4 . 3 . 235–46 . May 1999 . 10395213 . 10.1038/sj.mp.4000522. free .
  2. Basso AM, Gallagher KB, Bratcher NA, Brioni JD, Moreland RB, Hsieh GC, Drescher K, Fox GB, Decker MW, Rueter LE . Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test . Neuropsychopharmacology . 30 . 7 . 1257–68 . July 2005 . 15688083 . 10.1038/sj.npp.1300677 . free .

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