CORO1C explained

Coronin-1C is a protein that in humans is encoded by the CORO1C gene.^{[1] [2] [3]}

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Further reading

• Rosentreter A, Hofmann A, Xavier CP . Coronin 3 involvement in F-actin-dependent processes at the cell cortex . Exp. Cell Res. . 313 . 5 . 878–95 . 2007 . 17274980 . 10.1016/j.yexcr.2006.12.015 . etal. 10072/14982 . free .
• Rush J, Moritz A, Lee KA . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nat. Biotechnol. . 23 . 1 . 94–101 . 2005 . 15592455 . 10.1038/nbt1046 . 7200157 . etal.
• Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Spoerl Z, Stumpf M, Noegel AA, Hasse A . Oligomerization, F-actin interaction, and membrane association of the ubiquitous mammalian coronin 3 are mediated by its carboxyl terminus . J. Biol. Chem. . 277 . 50 . 48858–67 . 2003 . 12377779 . 10.1074/jbc.M205136200 . free .
• Iizaka M, Han HJ, Akashi H . Isolation and chromosomal assignment of a novel human gene, CORO1C, homologous to coronin-like actin-binding proteins . Cytogenet. Cell Genet. . 88 . 3–4 . 221–4 . 2000 . 10828594 . 10.1159/000015555 . 46548464 . etal.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 . etal.
• Wick M, Bürger C, Brüsselbach S . Identification of serum-inducible genes: different patterns of gene regulation during G0-->S and G1-->S progression . J. Cell Sci. . 107 . 1. 227–39 . 1994 . 10.1242/jcs.107.1.227 . 8175911 . etal.
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .

Notes and References

1. Okumura M, Kung C, Wong S, Rodgers M, Thomas ML . Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein . DNA Cell Biol . 17 . 9 . 779–87 . Oct 1998 . 9778037 . 10.1089/dna.1998.17.779 .
2. de Hostos EL . The coronin family of actin-associated proteins . Trends Cell Biol . 9 . 9 . 345–50 . Oct 1999 . 10461187 . 10.1016/S0962-8924(99)01620-7 .
3. Web site: Entrez Gene: CORO1C coronin, actin binding protein, 1C.