COPB1 explained

Coatomer subunit beta is a protein that in humans is encoded by the COPB1 gene.^[1]

See also

• COPI coatomer, a protein complex

Further reading

• Benichou S . Use of the two-hybrid system to identify cellular partners of the HIV1 Nef protein . Res. Virol. . 148 . 1 . 71–3 . 1997 . 9017839 . 10.1016/S0923-2516(97)81918-8 . vanc. Liu LX . Erdtmann L . 3 . Selig . L . Benarous . R .
• Geyer M, Fackler OT, Peterlin BM . Structure–function relationships in HIV-1 Nef . EMBO Rep. . 2 . 7 . 580–5 . 2001 . 11463741 . 10.1093/embo-reports/kve141 . 1083955 .
• Duden R . Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin . Cell . 64 . 3 . 649–65 . 1991 . 1840503 . 10.1016/0092-8674(91)90248-W . vanc. Griffiths G . Frank R . 3 . Argos . Patrick . Kreis . Thomas E. . 54293222 .
• Waters MG, Serafini T, Rothman JE . 'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles . Nature . 349 . 6306 . 248–51 . 1991 . 1898986 . 10.1038/349248a0 . 1991Natur.349..248W . 4342145 .
• Orcl L, Palmer DJ, Amherdt M, Rothman JE . Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol . Nature . 364 . 6439 . 732–4 . 1993 . 8355790 . 10.1038/364732a0 . 1993Natur.364..732O . 4348442 .
• Aniento F, Gu F, Parton RG, Gruenberg J . An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes . J. Cell Biol. . 133 . 1 . 29–41 . 1996 . 8601610 . 10.1083/jcb.133.1.29 . 2120778 .
• Lowe M, Kreis TE . In vivo assembly of coatomer, the COP-I coat precursor . J. Biol. Chem. . 271 . 48 . 30725–30 . 1997 . 8940050 . 10.1074/jbc.271.48.30725 . free .
• Hansen K . Association of coatomer proteins with the beta-receptor for platelet-derived growth factor . Biochem. Biophys. Res. Commun. . 235 . 3 . 455–60 . 1997 . 9207175 . 10.1006/bbrc.1997.6821 . vanc. Rönnstrand L . Rorsman C . 3 . Hellman . Ulf . Heldin . Carl-Henrik .
• Pavel J, Harter C, Wieland FT . Reversible dissociation of coatomer: Functional characterization of a β/δ-coat protein subcomplex . Proc. Natl. Acad. Sci. U.S.A. . 95 . 5 . 2140–5 . 1998 . 9482852 . 10.1073/pnas.95.5.2140 . 19276 . 1998PNAS...95.2140P . free .
• Piguet V . Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes . Cell . 97 . 1 . 63–73 . 1999 . 10199403 . 10.1016/S0092-8674(00)80715-1 . vanc. Gu F . Foti M . 3 . Demaurex . Nicolas . Gruenberg . Jean . Carpentier . Jean-Louis . Trono . Didier . 14793848 . free .
• Zhao L, Helms JB, Brunner J, Wieland FT . GTP-dependent binding of ADP-ribosylation factor to coatomer in close proximity to the binding site for dilysine retrieval motifs and p23 . J. Biol. Chem. . 274 . 20 . 14198–203 . 1999 . 10318838 . 10.1074/jbc.274.20.14198 . free .
• Fischer KD, Helms JB, Zhao L, Wieland FT . Site-specific photocrosslinking to probe interactions of Arf1 with proteins involved in budding of COPI vesicles . Methods . 20 . 4 . 455–64 . 2000 . 10720466 . 10.1006/meth.2000.0958 .
• Allan BB, Moyer BD, Balch WE . Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion . Science . 289 . 5478 . 444–8 . 2000 . 10903204 . 10.1126/science.289.5478.444 . 2000Sci...289..444A .
• Eugster A, Frigerio G, Dale M, Duden R . COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP . EMBO J. . 19 . 15 . 3905–17 . 2000 . 10921873 . 10.1093/emboj/19.15.3905 . 306616 .
• Sullivan BM . RGS4 and RGS2 Bind Coatomer and Inhibit COPI Association with Golgi Membranes and Intracellular Transport . Mol. Biol. Cell . 11 . 9 . 3155–68 . 2000 . 10982407 . 10.1091/mbc.11.9.3155. 14982 . vanc. Harrison-Lavoie KJ . Marshansky V . 3 . Lin . HY . Kehrl . JH . Ausiello . DA . Brown . D . Druey . KM .
• Futatsumori M . Identification and characterization of novel isoforms of COP I subunits . J. Biochem. . 128 . 5 . 793–801 . 2001 . 11056392 . 10.1093/oxfordjournals.jbchem.a022817. vanc. Kasai K . Takatsu H . 3 . Shin . HW . Nakayama . K .
• Hartley JL, Temple GF, Brasch MA . DNA Cloning Using In Vitro Site-Specific Recombination . Genome Res. . 10 . 11 . 1788–95 . 2001 . 11076863 . 10.1101/gr.143000 . 310948 .
• Wiemann S . Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs . Genome Res. . 11 . 3 . 422–35 . 2001 . 11230166 . 10.1101/gr.GR1547R . 311072 . vanc. Weil B . Wellenreuther R . 3 . Gassenhuber . J . Glassl . S . Ansorge . W . Böcher . M . Blöcker . H . Bauersachs . S .

External links

• • PDBe-KB provides an overview of all the structure information available in the PDB for Mouse Coatomer subunit beta

Notes and References

1. Benichou S, Bomsel M, Bodeus M, Durand H, Doute M, Letourneur F, Camonis J, Benarous R . Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic . J Biol Chem . 269 . 48 . 30073–6 . Dec 1994 . 10.1016/S0021-9258(18)43773-8 . 7982906 . free .