COMMD1 explained

COMM domain-containing protein 1 is a protein that is encoded by the COMMD1 gene in humans. It was originally regarded as Murr1 before being differentiated and renamed by Dr. Ezra Burstein's Lab^{[1] [2] [3]}

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 . etal.
• Harrington JJ, Sherf B, Rundlett S . Creation of genome-wide protein expression libraries using random activation of gene expression. . Nat. Biotechnol. . 19 . 5 . 440–5 . 2001 . 11329013 . 10.1038/88107 . 25064683 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Müller T, van de Sluis B, Zhernakova A . The canine copper toxicosis gene MURR1 does not cause non-Wilsonian hepatic copper toxicosis. . J. Hepatol. . 38 . 2 . 164–8 . 2003 . 12547404 . 10.1016/S0168-8278(02)00356-2 . etal.
• Tao TY, Liu F, Klomp L . The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein. . J. Biol. Chem. . 278 . 43 . 41593–6 . 2004 . 12968035 . 10.1074/jbc.C300391200 . etal. free .
• Klomp AE, van de Sluis B, Klomp LW, Wijmenga C . The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis. . J. Hepatol. . 39 . 5 . 703–9 . 2004 . 14568250 . 10.1016/S0168-8278(03)00380-5 .
• Biasio W, Chang T, McIntosh CJ, McDonald FJ . Identification of Murr1 as a regulator of the human delta epithelial sodium channel. . J. Biol. Chem. . 279 . 7 . 5429–34 . 2004 . 14645214 . 10.1074/jbc.M311155200 . free .
• Ganesh L, Burstein E, Guha-Niyogi A . The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. . Nature . 426 . 6968 . 853–7 . 2004 . 14685242 . 10.1038/nature02171 . 2024-04-25 . etal. 2027.42/62709 . 4344050 . free .
• Burstein E, Ganesh L, Dick RD . A novel role for XIAP in copper homeostasis through regulation of MURR1. . EMBO J. . 23 . 1 . 244–54 . 2004 . 14685266 . 10.1038/sj.emboj.7600031 . 1271669 . etal.
• Stuehler B, Reichert J, Stremmel W, Schaefer M . Analysis of the human homologue of the canine copper toxicosis gene MURR1 in Wilson disease patients. . J. Mol. Med. . 82 . 9 . 629–34 . 2005 . 15205742 . 10.1007/s00109-004-0557-9 . 8184776 .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Burstein E, Hoberg JE, Wilkinson AS . COMMD proteins, a novel family of structural and functional homologs of MURR1. . J. Biol. Chem. . 280 . 23 . 22222–32 . 2005 . 15799966 . 10.1074/jbc.M501928200 . etal. free .
• Coronado VA, Bonneville JA, Nazer H . COMMD1 (MURR1) as a candidate in patients with copper storage disease of undefined etiology. . Clin. Genet. . 68 . 6 . 548–51 . 2006 . 16283886 . 10.1111/j.1399-0004.2005.00524.x . 27815621 . etal.
• Zhang Z, Joh K, Yatsuki H . Comparative analyses of genomic imprinting and CpG island-methylation in mouse Murr1 and human MURR1 loci revealed a putative imprinting control region in mice. . Gene . 366 . 1 . 77–86 . 2006 . 16305817 . 10.1016/j.gene.2005.08.020 . etal.
• de Bie P, van de Sluis B, Burstein E . Characterization of COMMD protein-protein interactions in NF-kappaB signalling. . Biochem. J. . 398 . 1 . 63–71 . 2006 . 16573520 . 10.1042/BJ20051664 . 1525016 . etal.
• Sommerhalter M, Zhang Y, Rosenzweig AC . Solution structure of the COMMD1 N-terminal domain. . J. Mol. Biol. . 365 . 3 . 715–21 . 2007 . 17097678 . 10.1016/j.jmb.2006.10.030 . 2706016 .
• Maine GN, Mao X, Komarck CM, Burstein E . COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. . EMBO J. . 26 . 2 . 436–47 . 2007 . 17183367 . 10.1038/sj.emboj.7601489 . 1783443 .

Notes and References

1. Nabetani A, Hatada I, Morisaki H, Oshimura M, Mukai T . Mouse U2af1-rs1 is a neomorphic imprinted gene . Mol Cell Biol . 17 . 2 . 789–98 . Feb 1997 . 9001233 . 231805 . 10.1128/mcb.17.2.789.
2. van De Sluis B, Rothuizen J, Pearson PL, van Oost BA, Wijmenga C . Identification of a new copper metabolism gene by positional cloning in a purebred dog population . Hum Mol Genet . 11 . 2 . 165–73 . Jan 2002 . 11809725 . 10.1093/hmg/11.2.165 . free .
3. Web site: Entrez Gene: COMMD1 copper metabolism (Murr1) domain containing 1.