CLRN1-AS1 explained

In molecular biology, CLRN1 antisense RNA 1 (CLRN1-AS1) (previously known as clarin 1 opposite strand, CLRN1OS or USH critical region pseudogene, UCRP) is a human gene encoding a long non-coding RNA. It was originally identified in a screen to identify the genes responsible for Usher syndrome type 3 and presumed to be an unprocessed pseudogene.^[1]

See also

• Long non-coding RNA

Further reading

• Joensuu T, Hämäläinen R, Yuan B . Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3. . Am. J. Hum. Genet. . 69 . 4 . 673–684 . 2001 . 11524702 . 10.1086/323610 . 1226054. etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–45 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Västinsalo H, Jalkanen R, Dinculescu A . Alternative splice variants of the USH3A gene Clarin 1 (CLRN1). . Eur. J. Hum. Genet. . 19 . 1 . 30–35 . 2011 . 20717163 . 10.1038/ejhg.2010.140 . 3039507. etal.

Notes and References

1. Joensuu . T. . Hämäläinen . R. . Yuan . B. . Johnson . C. . Tegelberg . S. . Gasparini . P. . Zelante . L. . Pirvola . U. . Pakarinen . L. . Lehesjoki . 10.1086/323610 . A. E. . De La Chapelle . A. . Sankila . E. M. . Mutations in a Novel Gene with Transmembrane Domains Underlie Usher Syndrome Type 3 . The American Journal of Human Genetics . 69 . 4 . 673–684 . 2001 . 11524702 . 1226054 .