CLDN12 explained

Claudin-12 is a protein that in humans is encoded by the CLDN12 gene.^[1] It belongs to the group of claudins.

Further reading

• Kniesel U, Wolburg H . Tight junctions of the blood–brain barrier. . Cell. Mol. Neurobiol. . 20 . 1 . 57–76 . 2000 . 10690502 . 10.1023/A:1006995910836 . 26473781 .
• Heiskala M, Peterson PA, Yang Y . The roles of claudin superfamily proteins in paracellular transport. . Traffic . 2 . 2 . 93–8 . 2001 . 11247307 . 10.1034/j.1600-0854.2001.020203.x . 12132159 . free .
• Tsukita S, Furuse M, Itoh M . Multifunctional strands in tight junctions. . Nat. Rev. Mol. Cell Biol. . 2 . 4 . 285–93 . 2001 . 11283726 . 10.1038/35067088 . 36524601 .
• Tsukita S, Furuse M . Claudin-based barrier in simple and stratified cellular sheets. . Curr. Opin. Cell Biol. . 14 . 5 . 531–6 . 2003 . 12231346 . 10.1016/S0955-0674(02)00362-9 .
• González-Mariscal L, Betanzos A, Nava P, Jaramillo BE . Tight junction proteins. . Prog. Biophys. Mol. Biol. . 81 . 1 . 1–44 . 2003 . 12475568 . 10.1016/S0079-6107(02)00037-8 . free .
• Hartley JL, Temple GF, Brasch MA . DNA cloning using in vitro site-specific recombination. . Genome Res. . 10 . 11 . 1788–95 . 2001 . 11076863 . 10.1101/gr.143000 . 310948 .
• Wiemann S, Weil B, Wellenreuther R . Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. . Genome Res. . 11 . 3 . 422–35 . 2001 . 11230166 . 10.1101/gr.GR1547R . 311072 . etal.
• Niimi T, Nagashima K, Ward JM . claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing. . Mol. Cell. Biol. . 21 . 21 . 7380–90 . 2001 . 11585919 . 10.1128/MCB.21.21.7380-7390.2001 . 99911 . etal.
• Kiuchi-Saishin Y, Gotoh S, Furuse M . Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. . J. Am. Soc. Nephrol. . 13 . 4 . 875–86 . 2002 . 10.1681/ASN.V134875 . 11912246 . etal. free .
• Brandner JM, Kief S, Grund C . Organization and formation of the tight junction system in human epidermis and cultured keratinocytes. . Eur. J. Cell Biol. . 81 . 5 . 253–63 . 2003 . 12067061 . 10.1078/0171-9335-00244 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Scherer SW, Cheung J, MacDonald JR . Human chromosome 7: DNA sequence and biology. . Science . 300 . 5620 . 767–72 . 2003 . 12690205 . 2882961 . 10.1126/science.1083423 . 2003Sci...300..767S . etal.
• Hillier LW, Fulton RS, Fulton LA . The DNA sequence of human chromosome 7. . Nature . 424 . 6945 . 157–64 . 2003 . 12853948 . 10.1038/nature01782 . 2003Natur.424..157H . etal. free .
• Kitajiri SI, Furuse M, Morita K . Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. . Hear. Res. . 187 . 1–2 . 25–34 . 2004 . 14698084 . 10.1016/S0378-5955(03)00338-1 . 31183039 . etal.
• Acharya P, Beckel J, Ruiz WG . Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. . Am. J. Physiol. Renal Physiol. . 287 . 2 . F305–18 . 2004 . 15068973 . 10.1152/ajprenal.00341.2003 . etal.
• Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS . A systems proteomics view of the endogenous human claudin protein family . J Proteome Res . 2015 . 15 . 2 . 339–359 . 26680015 . 10.1021/acs.jproteome.5b00769 . 4777318 .

Notes and References

1. Web site: Entrez Gene: CLDN12 claudin 12.