CIRBP explained
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene.[1] [2] [3] The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia.
Further reading
- Sheikh MS . Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein . J. Biol. Chem. . 272 . 42 . 26720–6 . 1997 . 9334257 . 10.1074/jbc.272.42.26720 . vanc. Carrier F . Papathanasiou MA . 3 . Hollander . MC . Zhan . Q . Yu . K . Fornace Jr . AJ . free .
- Nishiyama H . Decreased expression of cold-inducible RNA-binding protein (CIRP) in male germ cells at elevated temperature . Am. J. Pathol. . 152 . 1 . 289–96 . 1998 . 9422546 . 1858111 . vanc. Danno S . Kaneko Y . 3 . Itoh . K . Yokoi . H . Fukumoto . M . Okuno . H . Millán . JL . Matsuda . T .
- Lee J, Bedford MT . PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays . EMBO Rep. . 3 . 3 . 268–73 . 2002 . 11850402 . 10.1093/embo-reports/kvf052 . 1084016 .
- Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
- Hamid AA . Expression of cold-inducible RNA-binding protein in the normal endometrium, endometrial hyperplasia, and endometrial carcinoma . Int. J. Gynecol. Pathol. . 22 . 3 . 240–7 . 2004 . 12819390 . 10.1097/01.PGP.0000070851.25718.EC . vanc. Mandai M . Fujita J . 3 . Nanbu . Kanako . Kariya . Masatoshi . Kusakari . Takashi . Fukuhara . Ken . Fujii . Shingo . 22639276 .
- Ota T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . vanc. Suzuki Y . Nishikawa T . 3 . Otsuki . Tetsuji . Sugiyama . Tomoyasu . Irie . Ryotaro . Wakamatsu . Ai . Hayashi . Koji . Sato . Hiroyuki . free .
- Grimwood J . The DNA sequence and biology of human chromosome 19 . Nature . 428 . 6982 . 529–35 . 2004 . 15057824 . 10.1038/nature02399 . vanc. Gordon LA . Olsen A . 3 . Terry . Astrid . Schmutz . Jeremy . Lamerdin . Jane . Hellsten . Uffe . Goodstein . David . Couronne . Olivier . 2004Natur.428..529G . free .
- Wellmann S . Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism . J. Cell Sci. . 117 . Pt 9 . 1785–94 . 2004 . 15075239 . 10.1242/jcs.01026 . vanc. Bührer C . Moderegger E . 3 . Zelmer . A . Kirschner . R . Koehne . P . Fujita . J . Seeger . K . free .
- Gerhard DS . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
- Rual JF . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . vanc. Venkatesan K . Hao T . 3 . Hirozane-Kishikawa . Tomoko . Dricot . Amélie . Li . Ning . Berriz . Gabriel F. . Gibbons . Francis D. . Dreze . Matija . 2005Natur.437.1173R . 4427026 .
- Lim J . A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration . Cell . 125 . 4 . 801–14 . 2006 . 16713569 . 10.1016/j.cell.2006.03.032 . vanc. Hao T . Shaw C . 3 . Patel . Akash J. . Szabó . Gábor . Rual . Jean-François . Fisk . C. Joseph . Li . Ning . Smolyar . Alex . 13709685 . free .
- Ewing RM . Large-scale mapping of human protein–protein interactions by mass spectrometry . Mol. Syst. Biol. . 3 . 1. 89 . 2007 . 17353931 . 10.1038/msb4100134 . 1847948 . vanc. Chu P . Elisma F . 3 . Li . Hongyan . Taylor . Paul . Climie . Shane . McBroom-Cerajewski . Linda . Robinson . Mark D . O'Connor . Liam .
Notes and References
- Nishiyama H, Higashitsuji H, Yokoi H, Itoh K, Danno S, Matsuda T, Fujita J . Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene . Gene . 204 . 1–2 . 115–20 . Feb 1998 . 9434172 . 10.1016/S0378-1119(97)00530-1 .
- Nishiyama H, Itoh K, Kaneko Y, Kishishita M, Yoshida O, Fujita J . A Glycine-rich RNA-binding Protein Mediating Cold-inducible Suppression of Mammalian Cell Growth . J Cell Biol . 137 . 4 . 899–908 . Jun 1997 . 9151692 . 2139845 . 10.1083/jcb.137.4.899 .
- Web site: Entrez Gene: CIRBP cold inducible RNA binding protein.