CIBERSORT explained

CIBERSORT, also called CIBERSORTx, is a bioinformatics tool used to deconvolute cell type proportions and gene expression profiles from bulk RNA sequencing datasets.[1] [2] It is among the fastest growing software tools in the life sciences.[3]

Notes and References

  1. Newman . Aaron M. . Liu . Chih Long . Green . Michael R. . Gentles . Andrew J. . Feng . Weiguo . Xu . Yue . Hoang . Chuong D. . Diehn . Maximilian . Alizadeh . Ash A. . 2015 . Robust enumeration of cell subsets from tissue expression profiles . Nature Methods . en . 12 . 5 . 453–457 . 10.1038/nmeth.3337 . 1548-7105. 4739640 .
  2. Newman . Aaron M. . Steen . Chloé B. . Liu . Chih Long . Gentles . Andrew J. . Chaudhuri . Aadel A. . Scherer . Florian . Khodadoust . Michael S. . Esfahani . Mohammad S. . Luca . Bogdan A. . Steiner . David . Diehn . Maximilian . Alizadeh . Ash A. . 2019 . Determining cell type abundance and expression from bulk tissues with digital cytometry . Nature Biotechnology . en . 37 . 7 . 773–782 . 10.1038/s41587-019-0114-2 . 1546-1696. 6610714 .
  3. Hutson . Matthew . 2023-01-12 . Hunting for the best bioscience software tool? Check this database . Nature . en . 10.1038/d41586-023-00053-w.

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