CHST2 explained

Carbohydrate sulfotransferase 2 is an enzyme that in humans is encoded by the CHST2 gene.^{[1] [2]}

Further reading

• Bernstein HB, Compans RW . Sulfation of the human immunodeficiency virus envelope glycoprotein. . J. Virol. . 66 . 12 . 6953–9 . 1992 . 1433500 . 10.1128/JVI.66.12.6953-6959.1992. 240329 .
• Shilatifard A, Merkle RK, Helland DE . Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine. . J. Virol. . 67 . 2 . 943–52 . 1993 . 8419650 . 10.1128/JVI.67.2.943-952.1993. 237448 . etal.
• Uchimura K, Muramatsu H, Kadomatsu K . Molecular cloning and characterization of an N-acetylglucosamine-6-O-sulfotransferase. . J. Biol. Chem. . 273 . 35 . 22577–83 . 1998 . 9712885 . 10.1074/jbc.273.35.22577 . etal. free .
• Uchimura K, Muramatsu H, Kaname T . Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells. . J. Biochem. . 124 . 3 . 670–8 . 1998 . 9722682 . 10.1093/oxfordjournals.jbchem.a022164. etal.
• Tu L, Murphy PG, Li X, Tedder TF . L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1. . J. Immunol. . 163 . 9 . 5070–8 . 1999 . 10.4049/jimmunol.163.9.5070 . 10528213 . free .
• Sakaguchi H, Kitagawa H, Sugahara K . Functional expression and genomic structure of human N-acetylglucosamine-6-O-sulfotransferase that transfers sulfate to beta-N-acetylglucosamine at the nonreducing end of an N-acetyllactosamine sequence. . Biochim. Biophys. Acta . 1523 . 2–3 . 269–76 . 2000 . 11042394 . 10.1016/s0304-4165(00)00136-7.
• Okuda T, Mita S, Yamauchi S . Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase. . J. Biochem. . 128 . 5 . 763–70 . 2001 . 11056388 . 10.1093/oxfordjournals.jbchem.a022813. etal.
• Li X, Tu L, Murphy PG . CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin. . J. Leukoc. Biol. . 69 . 4 . 565–74 . 2001 . 10.1189/jlb.69.4.565 . 11310842 . 8888883 . etal. free .
• Uchimura K, El-Fasakhany FM, Hori M . Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression. . J. Biol. Chem. . 277 . 6 . 3979–84 . 2002 . 11726653 . 10.1074/jbc.M106587200 . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Grunwell JR, Rath VL, Rasmussen J . Characterization and mutagenesis of Gal/GlcNAc-6-O-sulfotransferases. . Biochemistry . 41 . 52 . 15590–600 . 2003 . 12501187 . 10.1021/bi0269557 . etal.
• de Graffenried CL, Bertozzi CR . Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis. . J. Biol. Chem. . 278 . 41 . 40282–95 . 2003 . 12855678 . 10.1074/jbc.M304928200 . free .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• de Graffenried CL, Bertozzi CR . The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity. . J. Biol. Chem. . 279 . 38 . 40035–43 . 2004 . 15220337 . 10.1074/jbc.M405709200 . free .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Chen L, Ichihara-Tanaka K, Muramatsu T . Role of the carboxyl-terminal region in the activity of N-acetylglucosamine 6-o-sulfotransferase-1. . J. Biochem. . 136 . 5 . 659–64 . 2005 . 15632306 . 10.1093/jb/mvh162 .
• Kanoh A, Seko A, Ideo H . Ectopic expression of N-acetylglucosamine 6-O-sulfotransferase 2 in chemotherapy-resistant ovarian adenocarcinomas. . Glycoconj. J. . 23 . 5–6 . 453–60 . 2007 . 16897186 . 10.1007/s10719-006-6979-6 . 22628478 . etal.

Notes and References

1. Li X, Tedder TF . CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization . Genomics . 55 . 3 . 345–7 . May 1999 . 10049591 . 10.1006/geno.1998.5653 .
2. Web site: Entrez Gene: CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2.