CFHR2 explained
Complement factor H-related protein 2 is a protein that in humans is encoded by the CFHR2 gene.[1] [2] [3]
Further reading
- Zipfel PF, Skerka C . Complement factor H and related proteins: an expanding family of complement-regulatory proteins? . Immunol. Today . 15 . 3 . 121–6 . 1994 . 8172644 . 10.1016/0167-5699(94)90155-4 .
- Hageman GS, Hancox LS, Taiber AJ . Extended Haplotypes in the Complement Factor H (CFH) and CFH-related (CFHR) Family of Genes that Protect against Age-related Macular Degeneration: Identification, Ethnic Distribution and Evolutionary Implications . Ann. Med. . 38 . 8 . 592–604 . 2007 . 17438673 . 10.1080/07853890601097030 . 1905836 . etal.
- Gregory SG, Barlow KF, McLay KE . The DNA sequence and biological annotation of human chromosome 1 . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . 2006Natur.441..315G . etal. free .
- Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
- Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
- Díaz-Guillén MA, Rodríguez de Córdoba S, Heine-Suñer D . A radiation hybrid map of complement factor H and factor H-related genes . Immunogenetics . 49 . 6 . 549–52 . 1999 . 10380701 . 10.1007/s002510050534 . 31776506 .
- Skerka C, Horstmann RD, Zipfel PF . Molecular cloning of a human serum protein structurally related to complement factor H . J. Biol. Chem. . 266 . 18 . 12015–20 . 1991 . 10.1016/S0021-9258(18)99058-7 . 1711047 . free .
Notes and References
- Skerka C, Timmann C, Horstmann RD, Zipfel PF . Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes . J Immunol . 148 . 10 . 3313–8 . Jun 1992 . 10.4049/jimmunol.148.10.3313 . 1533657 . 25372557 .
- Skerka C, Moulds JM, Taillon-Miller P, Hourcade D, Zipfel PF . The human factor H-related gene 2 (FHR2): structure and linkage to the coagulation factor XIIIb gene . Immunogenetics . 42 . 4 . 268–74 . Oct 1995 . 7672821 . 10.1007/bf00176444. 19760957 .
- Web site: Entrez Gene: CFHR2 complement factor H-related 2.