CEP135 explained

Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene.^{[1] [2] [3]} It is part of the centrosome throughout the cell cycle, being distributed in the pericentriolar material.^[4] CEP135 is required for the centriolar localization of CEP250.^[5]

External links

• • PDBe-KB provides an overview of all the structure information available in the PDB for Human Centrosomal protein of 135 kDa

Further reading

• Ewing RM, Chu P, Elisma F . Large-scale mapping of human protein–protein interactions by mass spectrometry . Mol. Syst. Biol. . 3 . 1. 89 . 2007 . 17353931 . 10.1038/msb4100134 . 1847948 . etal.
• Olsen JV, Blagoev B, Gnad F . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . etal. free .
• Colland F, Jacq X, Trouplin V . Functional Proteomics Mapping of a Human Signaling Pathway . Genome Res. . 14 . 7 . 1324–32 . 2004 . 15231748 . 10.1101/gr.2334104 . 442148 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery . Genome Res. . 6 . 9 . 791–806 . 1997 . 8889548 . 10.1101/gr.6.9.791 . free .

Notes and References

1. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O . Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro . DNA Res . 5 . 3 . 169–76 . Dec 1998 . 9734811 . 10.1093/dnares/5.3.169 . free .
2. Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M . Proteomic characterization of the human centrosome by protein correlation profiling . Nature . 426 . 6966 . 570–4 . Dec 2003 . 14654843 . 10.1038/nature02166 . 2003Natur.426..570A . 4427303 .
3. Web site: Entrez Gene: CEP135 centrosomal protein 135kDa.
4. Ohta T, Essner R, Ryu JH, Palazzo RE, Uetake Y, Kuriyama R . Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells . J. Cell Biol. . 156 . 1 . 87–99 . January 2002 . 11781336 . 2173569 . 10.1083/jcb.200108088 .
5. Kim K, Lee S, Chang J, Rhee K . A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization . Exp. Cell Res. . 314 . 20 . 3692–700 . December 2008 . 18851962 . 10.1016/j.yexcr.2008.09.016 .