CD 205 explained

CD205 also called Lymphocyte antigen 75 is a protein that in humans is encoded by the LY75 gene.^{[1] [2]}

CD205 is also known as DEC-205.

Further reading

• Tungekar MF, Gatter KC, Ritter MA . Bladder carcinomas and normal urothelium universally express gp200-MR6, a molecule functionally associated with the interleukin 4 receptor (CD 124) . Br. J. Cancer . 73 . 4 . 429–32 . 1996 . 8595155 . 10.1038/bjc.1996.77. 2074450 .
• al-Tubuly AA . Differential expression of gp200-MR6 molecule in benign hyperplasia and down-regulation in invasive carcinoma of the breast . Br. J. Cancer . 74 . 7 . 1005–11 . 1996 . 8855966 . 10.1038/bjc.1996.481. 2077117 . vanc. Luqmani YA . Shousha S . 3 . Melcher . D . Ritter . MA .
• McKay PF . The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family . Eur. J. Immunol. . 28 . 12 . 4071–83 . 1999 . 9862343 . 10.1002/(SICI)1521-4141(199812)28:12<4071::AID-IMMU4071>3.0.CO;2-O . vanc. Imami N . Johns M . 3 . Taylor-Fishwick . David A. . Sedibane . Lucas M. . Totty . Nicholas F. . Hsuan . J. Justin . Palmer . Donald B. . George . Andrew J. T. . 13656389 .
• Palmer DB . Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development . Immunology . 96 . 2 . 236–45 . 1999 . 10233701 . 10.1046/j.1365-2567.1999.00691.x . 2326733 . vanc. Crompton T . Marandi MB . 3 . George . Ritter . AJ . MA .
• Guo M . A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells . Hum. Immunol. . 61 . 8 . 729–38 . 2000 . 10980384 . 10.1016/S0198-8859(00)00144-0 . vanc. Gong S . Maric S . 3 . Misulovin . Ziva . Pack . Maggi . Mahnke . Karsten . Nussenzweig . Michel C . Steinman . Ralph M .
• Kato M . Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells . Int. Immunol. . 12 . 11 . 1511–9 . 2000 . 11058570 . 10.1093/intimm/12.11.1511 . vanc. Neil TK . Fearnley DB . 3 . McLellan . AD . Vuckovic . S . Hart . DN . free .
• Kato M . Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1 . J. Biol. Chem. . 278 . 36 . 34035–41 . 2003 . 12824192 . 10.1074/jbc.M303112200 . vanc. Khan S . Gonzalez N . 3 . O'Neill . BP . McDonald . KJ . Cooper . BJ . Angel . NZ . Hart . DN . free .
• Bozzacco L . DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes . Proc. Natl. Acad. Sci. U.S.A. . 104 . 4 . 1289–94 . 2007 . 17229838 . 10.1073/pnas.0610383104 . 1783096 . 2007PNAS..104.1289B . vanc. Trumpfheller C . Siegal FP . 3 . Mehandru . S. . Markowitz . M. . Carrington . M. . Nussenzweig . M. C. . Piperno . A. G. . Steinman . R. M. . free .
• Nonaka D, Henley JD, Chiriboga L, Yee H . Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms . Am. J. Surg. Pathol. . 31 . 7 . 1038–44 . 2007 . 17592270 . 10.1097/PAS.0b013e31802b4917 . 30502411 .

Notes and References

1. Kato M, Neil TK, Clark GJ, Morris CM, Sorg RV, Hart DN . cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells . Immunogenetics . 47 . 6 . 442–50 . Jun 1998 . 9553150 . 10.1007/s002510050381 . 10949216 .
2. Web site: Entrez Gene: LY75 lymphocyte antigen 75.