CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase explained
| CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase |
| Ec Number: | 2.7.8.5 |
| Cas Number: | 9068-49-9 |
| Go Code: | 0008444 |
| Altnames: | - glycerophosphate phosphatidyltransferase
- 3-phosphatidyl-1'-glycerol-3'-phosphate synthase
- CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase
- cytidine 5'-diphospho-1,2-diacyl-sn-glycerol
- (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase
- phosphatidylglycerophosphate synthase
- phosphatidylglycerolphosphate synthase
- PGP synthase
- CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase
- CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase
- glycerol phosphate phosphatidyltransferase
- glycerol 3-phosphate phosphatidyltransferase
- phosphatidylglycerol phosphate synthase
- phosphatidylglycerol phosphate synthetase
- phosphatidylglycerophosphate synthetase
- sn-glycerol-3-phosphate phosphatidyltransferase
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In enzymology, a CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase is an enzyme that catalyzes the chemical reaction
CDP-diacylglycerol + sn-glycerol 3-phosphate
CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate
Thus, the two substrates of this enzyme are CDP-diacylglycerol and sn-glycerol 3-phosphate, whereas its two products are CMP and 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. This enzyme participates in glycerophospholipid metabolism.
References
- Bleasdale JE, Johnston JM . 1982 . CMP-dependent incorporation of [14C]Glycerol 3-phosphate into phosphatidylglycerol and phosphatidylglycerol phosphate by rabbit lung microsomes . Biochim. Biophys. Acta . 710 . 377 - 90 . 7074121 . 3 . 10.1016/0005-2760(82)90121-7.
- Hirabayashi T, Larson TJ, Dowhan W . 1976 . Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: purification by substrate affinity chromatography on cytidine 5'-diphospho-1,2-diacyl-sn-glycerol sepharose . Biochemistry . 15 . 5205 - 11 . 793612 . 10.1021/bi00669a002 . 24 .
