CDP-abequose synthase explained

CDP-abequose synthase
Ec Number:	1.1.1.341

CDP-abequose synthase (rfbJ (gene)) is an enzyme with systematic name CDP-alpha-D-abequose:NADP⁺ 4-oxidoreductase.^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

CDP-alpha-D-abequose + NADP⁺

\rightleftharpoons CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H⁺

This enzyme is from Yersinia pseudotuberculosis and Salmonella enterica.

Notes and References

1. Kessler AC, Brown PK, Romana LK, Reeves PR . Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose . Journal of General Microbiology . 137 . 12 . 2689–95 . December 1991 . 1724263 . 10.1099/00221287-137-12-2689 . free .
2. Wyk P, Reeves P . Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase . Journal of Bacteriology . 171 . 10 . 5687–93 . October 1989 . 2793832 . 210415 .
3. Thorson JS, Lo SF, Ploux O, He X, Liu HW . Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA . Journal of Bacteriology . 176 . 17 . 5483–93 . September 1994 . 8071227 . 196737 .