CD2BP2 explained

CD2 antigen cytoplasmic tail-binding protein 2 is a protein that in humans is encoded by the CD2BP2 gene.^{[1] [2]}

Interactions

CD2BP2 has been shown to interact with CD2.

Further reading

• Ewing RM, Chu P, Elisma F . Large-scale mapping of human protein-protein interactions by mass spectrometry. . Mol. Syst. Biol. . 3 . 1. 89 . 2007 . 17353931 . 10.1038/msb4100134 . 1847948 . etal.
• Olsen JV, Blagoev B, Gnad F . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . etal. free .
• Rual JF, Venkatesan K, Hao T . Towards a proteome-scale map of the human protein-protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 . etal.
• Laggerbauer B, Liu S, Makarov E . The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation. . RNA . 11 . 5 . 598–608 . 2005 . 15840814 . 10.1261/rna.2300805 . 1370748 . etal.
• Cohavy O, Zhou J, Ware CF, Targan SR . LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling. . J. Immunol. . 174 . 2 . 646–53 . 2005 . 15634882 . 10.4049/jimmunol.174.2.646. free .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Kofler M, Heuer K, Zech T, Freund C . Recognition sequences for the GYF domain reveal a possible spliceosomal function of CD2BP2. . J. Biol. Chem. . 279 . 27 . 28292–7 . 2004 . 15105431 . 10.1074/jbc.M402008200 . free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Freund C, Kühne R, Yang H . Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules. . EMBO J. . 21 . 22 . 5985–95 . 2003 . 12426371 . 10.1093/emboj/cdf602 . 137194 . etal.
• Hirosawa M, Nagase T, Ishikawa K . Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. . DNA Res. . 6 . 5 . 329–36 . 2000 . 10574461 . 10.1093/dnares/6.5.329 . etal. free .
• Freund C, Dötsch V, Nishizawa K . The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences. . Nat. Struct. Biol. . 6 . 7 . 656–60 . 1999 . 10404223 . 10.1038/10712 . 19688996 . etal.

Notes and References

1. Nishizawa K, Freund C, Li J, Wagner G, Reinherz EL . Identification of a proline-binding motif regulating CD2-triggered T lymphocyte activation . Proc Natl Acad Sci U S A . 95 . 25 . 14897–902 . Jan 1999 . 9843987 . 24547 . 10.1073/pnas.95.25.14897 . free .
2. Web site: Entrez Gene: CD2BP2 CD2 (cytoplasmic tail) binding protein 2.