CCT8 explained

T-complex protein 1 subunit theta is a protein that in humans is encoded by the CCT8 gene.^{[1] [2]} The CCT8 protein is a component of the TRiC complex.

See also

• TCP1, T-complex protein 1 subunit alpha
• Chaperonin

Further reading

• Nomura N, Miyajima N, Sazuka T . Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. . DNA Res. . 1 . 1 . 27–35 . 1995 . 7584026 . 10.1093/dnares/1.1.27 . etal. free .
• Nomura N, Miyajima N, Sazuka T . Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). . DNA Res. . 1 . 1 . 47–56 . 1995 . 7584028 . 10.1093/dnares/1.1.47 . etal. free .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Yamazaki M, Ono A, Watanabe K . Nucleotide sequence surrounding the locus marker D21S246 on human chromosome 21 . DNA Res. . 2 . 4 . 187–9 . 1996 . 8590283 . 10.1093/dnares/2.4.187 . etal. free .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 . etal.
• Scanlan MJ, Gordan JD, Williamson B . Antigens recognized by autologous antibody in patients with renal-cell carcinoma . Int. J. Cancer . 83 . 4 . 456–64 . 1999 . 10508479 . 10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 . etal. free .
• Hynes GM, Willison KR . Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin . J. Biol. Chem. . 275 . 25 . 18985–94 . 2000 . 10748209 . 10.1074/jbc.M910297199 . free .
• Hattori M, Fujiyama A, Taylor TD . The DNA sequence of human chromosome 21 . Nature . 405 . 6784 . 311–9 . 2000 . 10830953 . 10.1038/35012518 . 2000Natur.405..311H . etal. free .
• Yokota S, Yanagi H, Yura T, Kubota H . Cytosolic chaperonin-containing t-complex polypeptide 1 changes the content of a particular subunit species concomitant with substrate binding and folding activities during the cell cycle . Eur. J. Biochem. . 268 . 17 . 4664–73 . 2001 . 11532003 . 10.1046/j.1432-1327.2001.02393.x .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Imai Y, Soda M, Murakami T . A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death . J. Biol. Chem. . 278 . 51 . 51901–10 . 2004 . 14532270 . 10.1074/jbc.M309655200 . etal. free .
• Bouwmeester T, Bauch A, Ruffner H . A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway . Nat. Cell Biol. . 6 . 2 . 97–105 . 2004 . 14743216 . 10.1038/ncb1086 . 11683986 . etal.
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Rush J, Moritz A, Lee KA . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nat. Biotechnol. . 23 . 1 . 94–101 . 2005 . 15592455 . 10.1038/nbt1046 . 7200157 . etal.
• Wang L, Zhu YF, Guo XJ . A two-dimensional electrophoresis reference map of human ovary . J. Mol. Med. . 83 . 10 . 812–21 . 2006 . 16021519 . 10.1007/s00109-005-0676-y . 6644433 . etal.
• Hu YH, Warnatz HJ, Vanhecke D . Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins . BMC Genomics . 7. 155 . 2006 . 16780588 . 10.1186/1471-2164-7-155 . 1526728 . etal . free .
• Kim SC, Sprung R, Chen Y . Substrate and functional diversity of lysine acetylation revealed by a proteomics survey . Mol. Cell . 23 . 4 . 607–18 . 2006 . 16916647 . 10.1016/j.molcel.2006.06.026 . etal. free .

Notes and References

1. Kubota H, Hynes G, Willison K . The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1 . Gene . 154 . 2 . 231–6 . Apr 1995 . 7890169 . 10.1016/0378-1119(94)00880-2 .
2. Web site: Entrez Gene: CCT8 chaperonin containing TCP1, subunit 8 (theta).