CCPA (biochemistry) explained

2-Chloro-N6-cyclopentyladenosine (CCPA) is a specific receptor agonist for the Adenosine A1 receptor.[1] It is similar to N6-cyclopentyladenosine. Due to CCPA's high affinity for Adenosine A1 receptors, its tritiated derivative [<sup>3</sup>H]CCPA can be used as a diagnostic tool for detecting the receptors in tissue with low receptor density.

Notes and References

  1. Karl-Norbert Klotz. Martin J. Lohse. Ulrich Schwabe. Gloria Cristalli. Sauro Vittori. Mario Grifantini. 2-Chloro-N6-[3H]cyclopentyladenosine ([3HCCPA) — a high affinity agonist radioligand for A1 adenosine receptors|journal= Naunyn-Schmiedeberg's Archives of Pharmacology |volume = 340 |year = 1989 |issue=6 |pages = 679–683 |doi = 10.1007/BF00717744 |pmid=2615857 |s2cid=1114190 ].

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