CCNL1 explained

Cyclin-L1 is a protein that in humans is encoded by the CCNL1 gene.^{[1] [2]}

Further reading

• Zhang QH, Ye M, Wu XY . Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells . Genome Res. . 10 . 10 . 1546–60 . 2001 . 11042152 . 10.1101/gr.140200 . 310934 . etal.
• Berke JD, Sgambato V, Zhu PP . Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin . Neuron . 32 . 2 . 277–87 . 2001 . 11683997 . 10.1016/S0896-6273(01)00465-2 . 14486999 . etal. free .
• Redon R, Hussenet T, Bour G . Amplicon mapping and transcriptional analysis pinpoint cyclin L as a candidate oncogene in head and neck cancer . Cancer Res. . 62 . 21 . 6211–7 . 2002 . 12414649 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Clark HF, Gurney AL, Abaya E . The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 . etal.
• de Graaf K, Hekerman P, Spelten O . Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors . J. Biol. Chem. . 279 . 6 . 4612–24 . 2004 . 14623875 . 10.1074/jbc.M310794200 . etal. free .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Beausoleil SA, Jedrychowski M, Schwartz D . Large-scale characterization of HeLa cell nuclear phosphoproteins . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446 . 2004PNAS..10112130B . etal. free .
• Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Sticht C, Hofele C, Flechtenmacher C . Amplification of Cyclin L1 is associated with lymph node metastases in head and neck squamous cell carcinoma (HNSCC) . Br. J. Cancer . 92 . 4 . 770–4 . 2005 . 15700036 . 10.1038/sj.bjc.6602400 . 2361871 . etal.
• Muller D, Millon R, Théobald S . Cyclin L1 (CCNL1) gene alterations in human head and neck squamous cell carcinoma . Br. J. Cancer . 94 . 7 . 1041–4 . 2006 . 16598186 . 10.1038/sj.bjc.6603036 . 2361229 . etal.

Notes and References

1. Dickinson LA, Edgar AJ, Ehley J, Gottesfeld JM . Cyclin L is an RS domain protein involved in pre-mRNA splicing . J Biol Chem . 277 . 28 . 25465–73 . Jul 2002 . 11980906 . 10.1074/jbc.M202266200 . free .
2. Web site: Entrez Gene: CCNL1 cyclin L1.