CCDC80 explained

Coiled-coil domain-containing protein 80 is a protein that in humans is encoded by the CCDC80 gene.^{[1] [2] [3]} Bioinformatics analysis suggests the CCDC80 protein is a peroxiredoxin.^[4]

Further reading

• Okada T, Nishizawa H, Kurata A . URB is abundantly expressed in adipose tissue and dysregulated in obesity. . Biochem. Biophys. Res. Commun. . 367 . 2 . 370–6 . 2008 . 18178152 . 10.1016/j.bbrc.2007.12.164 . etal.
• Cha SY, Sung YK, Im S . URB expression in human dermal papilla cells. . J. Dermatol. Sci. . 39 . 2 . 128–30 . 2005 . 15998583 . 10.1016/j.jdermsci.2005.05.005 . etal.
• Bommer GT, Jäger C, Dürr EM . DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells. . J. Biol. Chem. . 280 . 9 . 7962–75 . 2005 . 15563452 . 10.1074/jbc.M412593200 . etal. free .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Aoki K, Sun YJ, Aoki S . Cloning, expression, and mapping of a gene that is upregulated in adipose tissue of mice deficient in bombesin receptor subtype-3. . Biochem. Biophys. Res. Commun. . 290 . 4 . 1282–8 . 2002 . 11812002 . 10.1006/bbrc.2002.6337 . etal.

Notes and References

1. Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery . Genome Res . 6 . 9 . 791–806 . May 1997 . 8889548 . 10.1101/gr.6.9.791 . free .
2. Liu Y, Monticone M, Tonachini L, Mastrogiacomo M, Marigo V, Cancedda R, Castagnola P . URB expression in human bone marrow stromal cells and during mouse development . Biochem Biophys Res Commun . 322 . 2 . 497–507 . Aug 2004 . 15325258 . 10.1016/j.bbrc.2004.07.161 .
3. Web site: Entrez Gene: CCDC80 coiled-coil domain containing 80.
4. Pawłowski K, Muszewska A, Lenart A . A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins. . BMC Genomics . 11 . 590 . 2010 . 20964819. 10.1186/1471-2164-11-590 . 3091736. etal . free .